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Biology-Related Homework Help Genetics and Developmental Biology Topic started by: stevehs on Nov 21, 2013



Title: why do DNA-binding proteins share common three dimensional motifs?
Post by: stevehs on Nov 21, 2013
why do DNA-binding proteins share common three dimensional motifs?
How do these common motifs allow proteins to locate specific DNA consensus sequences?


Title: Re: why do DNA-binding proteins share common three dimensional motifs?
Post by: adnlozano on Nov 21, 2013
HI is 1


Title: Re: why do DNA-binding proteins share common three dimensional motifs?
Post by: padre on Nov 21, 2013
I suppose you can say it's conserved. DNA binding proteins adopt a set of common three-dimensional structures called motifs.  Within these three dimensional motifs different proteins will have different specific amino acids that will recognize specific H-bond donor and acceptor sites on DNA.  In this way different DNA binding proteins can recognize very specific DNA sequences.

(http://www.ks.uiuc.edu/Research/pro_DNA/ster_horm_rec/binding.gif)