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Title: Loss-of-function mutations in tumour suppressor genes Post by: kiki-star on Nov 23, 2013 Loss-of-function mutations in tumour suppressor genes (choose any answers that apply):
a. are called oncogenes b. are called proto-oncogenes c. are recessive d. are dominant e. do not permit determination of the dominance relationship f. prevent cells from progressing to the next stage of the cell cycle g. prevent cell division h. promote progression to the next stage of the cell cycle i. promote cell division j. are heritable k. are not heritable Title: Re: Loss-of-function mutations in tumour suppressor genes Post by: padre on Nov 25, 2013 HI what did you end up putting for this? I'm shooting blanks reading through it.
Title: Re: Loss-of-function mutations in tumour suppressor genes Post by: kiki-star on Nov 25, 2013 I have the basic idea that in normal circumstances tumour suppressor genes stop cell division when something is awry. So when there is a loss of function mutation, it will allow cell division to progress no matter what. As for heritability and dominance still not sure...
Title: Re: Loss-of-function mutations in tumour suppressor genes Post by: padre on Nov 25, 2013 As for heritability and dominance still not sure... I suppose it wouldn't be unless it affected the reproductive cells. |