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Title: How does each SNP affect the targeting and processing of the insulin precursor Post by: nsch22 on Apr 24, 2014 How does each SNP affect the targeting and processing of the insulin precursor protein?
Recall that under normal circumstances, the insulin precursor protein is processed in the lumen of the ER to produce the mature (functional) insulin protein. Depending on the type of mutation produced and the protein domain affected, a SNP may have a profound effect on the structure and function of the mature insulin protein, or it may have no effect on the mature protein at all. In this exercise, you will use what you learned in the previous part to predict which domains will be present in the mature insulin protein produced by each patient. In addition, you will predict whether the insulin produced by each patient will function normally or whether the patient will exhibit some form of diabetes. For this exercise, assume that all patients are homozygous for the SNP. Drag blue labels to blue targets and pink labels to pink targets. Labels may be used once, more than once, or not at all. For help getting started, open the Hints. Please Help!! Attached is from the previous part Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: jvibo on Sep 30, 2014 By looking at the diagram one is able to conclude the following:
Patient 1: B Chain Patient 2: C Peptide Patient 3: Diabetic Site Patient 4: A Chain Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Cazimero on Oct 14, 2014 Thank you! Helped a lot
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: yungsavage on Oct 18, 2014 Thank You!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: asheesh14 on Oct 18, 2014 Sweet!! Thanks!!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: hignoffo on Oct 24, 2014 Thanks!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: meghanbr on Oct 24, 2014 thanks!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: xtasha on Oct 26, 2014 Thank you so much!!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: amitp014 on Oct 29, 2014 thank you so much
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: mojojojo1 on Oct 31, 2014 Thank you!!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: StevenChan on Nov 3, 2014 Content hidden
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Ujala on Nov 5, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: selenadhillon on Nov 8, 2014 Thank you very much!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: McJingles on Nov 18, 2014 Thanks helped a lot.
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: udahfiK on Nov 18, 2014 Thanks!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: fcku on Nov 20, 2014 thank u
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: User19 on Nov 21, 2014 Thanks!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: chemmy on Nov 21, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: 123teheh on Nov 22, 2014 thanks
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: syumul1 on Nov 23, 2014 thanks you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Biostudent7 on Nov 24, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: xeroaccuracy on Nov 26, 2014 THANK YOU!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: bljones on Nov 26, 2014 Thank You!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: soccerboy on Nov 26, 2014 thank you!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: inumaru90000 on Nov 28, 2014 thanks
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: lookitsme on Nov 29, 2014 Thanks a bunch
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: kaclar7988 on Nov 29, 2014 thank you!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: agoogledoogle on Nov 30, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: passion11381 on Nov 30, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: crusty13 on Nov 30, 2014 Fantastic thankyou!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: muckraker on Nov 30, 2014 thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: 2014bburns on Nov 30, 2014 Thanks
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Billyb0b on Dec 1, 2014 Thank you so much!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: domineek on Dec 1, 2014 thank you!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: succinum on Dec 3, 2014 Completely wrong!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: wakwakwakwa on Dec 4, 2014 thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: samsam12345 on Dec 4, 2014 Thank you!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: clairebear on Dec 7, 2014 THANK YOU!!!!!!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: iceejjfish on Dec 7, 2014 thank you please come again
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Meerona on Dec 7, 2014 Thank YOu
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: kaychips on Dec 7, 2014 thank youuu lol lol
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: datPMF on Dec 7, 2014 thanks so much
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: total on Dec 7, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: fedade on Dec 7, 2014 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: jp19 on Dec 8, 2014 thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: albotmccoy on Dec 9, 2014 Thank you!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: nicklauswood on Nov 23, 2015 This was one of the worst sections of Mastering Bio for me. Heres the answers for this section
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: eadfs on Dec 1, 2018 thanks you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: philip3084 on Feb 10, 2019 Thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: lholloway on Apr 10, 2019 thank you!!
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: henloo on May 5, 2019 thank you
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: henl on May 5, 2019 thanks
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: Tymur Melnyk on Feb 7, 2021 thanks osooo much
Title: Re: How does each SNP affect the targeting and processing of the insulin precursor Post by: samerin on Feb 21, 2021 thanks!
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