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Title: Probability that Kate & Clement's 1st child will be affected with rare disease? Post by: phyllidiela on Jul 5, 2014 Kate and Clement (II-4 & II-5) met while attending a conference. Their pedigrees are shown below (see attached jpeg file). They both have a sibling who has a rare human metabolic disease. They fall in love at first sight but are anxious about having kids because they know that the chance their first child will be affected is ____. Show your solution.
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