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Title: DNA polymerase catalyzes DNA strand elongation by removing what from the dNTPs? Post by: _12344 on Jul 25, 2014 I'm not sure. I know that dNTPs have three parts which are the nitrogenous base, a deoxyribose sugar, and a phosphate group. From the three components that is know I want to say that DNA polymerase can catalyze the DNA strand from elongation by removing the phosphate group from the dNTPs because the phosphate from a nucleotide will bond with 3' end of another nucleotide thus forming a phosphodiester bond. This formation is by dehydration synthesis.
I just want to see if I have the right points down, or if I am completely wrong in my explanation and reasoning. If I am I would greatly appreciate it if someone would steer me in the right direction. Title: Re: DNA polymerase catalyzes DNA strand elongation by removing what from the dNTPs? Post by: krystalskye on Jul 26, 2014 Yes, it removes 2 phosphates, leaving 1 phosphate that creates the phosphodiester bond between the two sugar molecules. The loss of two Pi releases energy needed to catalyze the elongation.
Pretty picture of it: http://what-when-how.com/wp-content/uploads/2011/05/tmp1E3124_thumb.jpg |