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Title: What is the replisome in DNA replication? Post by: ARomero13 on Jul 30, 2014 The enzymes responsible for DNA synthesis around the replication fork, joined into one large, multi-enzyme machine.
Title: Re: What is the replisome in DNA replication? Post by: f_zah1 on Aug 3, 2014 The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized.
Title: Re: What is the replisome in DNA replication? Post by: Ted.hb on Aug 6, 2014 a Replisome is an assembly of proteins bound together forming a molecular machinery. these protein assemblies are used to carry DNA replication.
Examples of the proteins of this complex are Helicase and DNA polymerase III. Helicase unwinds the DNA strands by breaking the hydrogen bonds between the nitrogenous bases of opposite nucleotides found on opposite strands. DNA polymerase III synthesises new strand complementary for each strand of the DNA. Note that all the proteins in a replisome work in harmony. for example, as the helicase continues unwinding a DNA strand, the DNA polymerase III would be synthesising new complementary strands for the unwinded strands that the helicase already passed on. |