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Biology-Related Homework Help Genetics and Developmental Biology Topic started by: kyrabunga on Feb 12, 2018



Title: Compare and contrast the two approaches to genome sequencing (whole-genome shotgun sequencing and ...
Post by: kyrabunga on Feb 12, 2018
Compare and contrast the two approaches to genome sequencing (whole-genome shotgun sequencing and clone-by-clone sequencing).
 
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Title: Compare and contrast the two approaches to genome sequencing (whole-genome shotgun sequencing and ...
Post by: russinhacker on Feb 12, 2018
Both approaches seek to completely cover an organism's entire genome and both require piecing together overlapping sequences.
WGS overlaps sequences after random fragmentation and sequencing of those fragments.
CBC use sequences from already overlapping chromosomal fragments.