Biology Forums - Study Force

Biology-Related Homework Help Nursing and Clinical Topic started by: Matyler98 on Feb 12, 2018



Title: A nurse has just learned that her child has a life-threatening complement disorder known as ...
Post by: Matyler98 on Feb 12, 2018
A nurse has just learned that her child has a life-threatening complement disorder known as hereditary angioneurotic edema (HAE). Due to deficiency in C1-INH, the nurse needs to be prepared for which possible life-threatening clinical manifestation?
 
  A)
  Bulging eyeballs
  B)
  Swelling of the airway
  C)
  Compressed carotid arteries
  D)
  Compression of brachial nerves


Title: A nurse has just learned that her child has a life-threatening complement disorder known as ...
Post by: frixion119 on Feb 12, 2018
Ans:
B

Feedback:

HAE is a rare, life-threatening complement disorder that results from deficiency of C1-inhibitor (HAE-C1-INH). It is an inherited autosomal dominant trait that causes mutation in the 11th chromosome. Deficiencies in C1-INH result in uncontrolled release of vasoactive substances that promote vascular permeability. The net result is the development of swelling in the subcutaneous tissues of the extremities, face/torso, or upper airway and GI tract. Laryngeal edema is a life-threatening manifestation that can lead to complete airway obstruction and death without interventions.