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Discussion News Articles and Discussion Topic started by: oemBiology on Dec 15, 2020



Title: How do hypoxia cause inflammation?
Post by: oemBiology on Dec 15, 2020
Referring to following link, I would like to know on how hypoxia cause inflammation and what the purpose of inflammation is.

Does anyone have any suggestions?
Thanks in advance


https://www.frontiersin.org/articles/10.3389/fimmu.2017.00324/full

Inflammation and environmental oxygen levels are linked; inflammation is often accompanied by hypoxia, and hypoxia itself can cause inflammation (7). In patients, many different inflamed tissues have been shown to have lower than normal oxygen levels. In the GI tract, mice with experimental models of inflammatory bowel disease (IBD) have increased inflammation and decreased oxygen levels in their colonic tissues (8), which corresponds with pathology observed in IBD patients (9). Examining the role of hypoxia in modulating epithelial cell and immune cell responses has been an area of active investigation in the design of new therapeutics for treating IBD (10).


Title: Re: How do hypoxia cause inflammation?
Post by: duddy on Dec 15, 2020
Hello oemBiology (https://biology-forums.com/index.php?action=profile;u=94679)

I found this article for you that explains the connection between the two:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930928/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831992/

Inflammation in the lungs, for example, causes hypoxia by forming pus between capillary wall and alveolus in the lung where the red blood cell transfer of O2 in and CO2 out normally takes place. Therefore, as inflammation continues over a period of days a patient develops hypoxia and may smother unless supplemental oxygen is furnished by means of a ventilator or O2 chamber.


Title: Re: How do hypoxia cause inflammation?
Post by: oemBiology on Dec 15, 2020
Do you know on what function of inflammation? Due to hypoxia, would body trigger inflammation in order to increase blood flow into this region and increase oxygen level? would it be the main purpose of inflammation?

Do you have any suggestions?
Thank you very much for any suggestions (^v^)


Title: Re: How do hypoxia cause inflammation?
Post by: oemBiology on Jan 28, 2021
Inflammation in the lungs, for example, causes hypoxia by forming pus between capillary wall and alveolus in the lung where the red blood cell transfer of O2 in and CO2 out normally takes place.

is phlegm a kind of pus within lung? if oxygen is provided, then inflammation would be gone by reducing pus production, correct?

Do you have any suggestions?
Thank you very much for any suggestions (^v^)


Title: Re: How do hypoxia cause inflammation?
Post by: bio_man on Jan 29, 2021
is phlegm a kind of pus within lung? if oxygen is provided, then inflammation would be gone by reducing pus production, correct?

Discharged phlegm, called sputum, can contain pus, composed of white blood cells, cellular debris, dead tissue, serous fluid, and viscous liquid (mucus). But the two words aren't interchangeable. Phlegm is produced by the lungs regularly, pus is produced in response to an infection.


Title: Re: How do hypoxia cause inflammation?
Post by: oemBiology on Jan 29, 2021
I would like to know on how to remove pus more efficient within body,

Do increasing blood circulation help to remove pus quickly within body? such as taking a sauna

Do you have any suggestions?
Thanks, to everyone very much for any suggestions (^v^)


Title: Re: How do hypoxia cause inflammation?
Post by: bio_man on Jan 29, 2021
I would like to know on how to remove pus more efficient within body,

Pus occurs as a result of infection. It consists of a buildup of dead, white blood cells that form when the body's immune system responds to the infection. If an infection occurs within the bloodstream, called septicemia, this is life-threatening, because the bacteria and their toxins can be carried through the bloodstream to your entire body.