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Biology-Related Homework Help Cell Biology Topic started by: Odiseizam on Mar 18, 2021



Title: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
Hi BiFo'ers I'll like to ask for opinions on this proposition, I know this is just overall overview, but think is good point for prevention mids pandemics ...

https://www.scienceforums.net/topic/124536-cbd-as-endocannabinoid-booster-of-t-cells/

https://www.thenakedscientists.com/forum/index.php?topic=81962.0



Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 18, 2021
Hi Odiseizam (https://biology-forums.com/index.php?action=profile;u=993690)

Have you read the following article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748879/

The Profile of Immune Modulation by Cannabidiol (CBD) Involves Deregulation of Nuclear Factor of Activated T Cells (NFAT)

Excerpt:

Taken together, these data suggest that CBD suppresses T cell function and that CB1 and/or CB2 play a critical role in the magnitude of the in vitro anti-sRBC IgM AFC response.

CBD possesses low affinity for both CB1 and CB2 cannabinoid receptors and therefore, does not produce the “high” associated with marijuana use [2, 3]. Despite this, CBD does exhibit immunosuppressive properties. In particular, CBD decreased IL-8 and the chemokines MIP-1α and MIP-1β from a human B cell line [4]. CBD has also been shown to suppress collagen-induced arthritis [5], and carrageenan-induced inflammation [6]. Importantly, CBD has been efficacious in combination with THC in treating neuropathic pain in multiple sclerosis, an autoimmune disease [7, 8].

Thoughts?


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
@bio_man  yes I am aware for the discrepancies in the studies, and in the second proposed NS link above in my first post I am suggesting that this is most probably due to synthetic CBD ...

this dont excludes the findings in the studies proposed in the first SF linked thread ... again ...

https://www.scienceforums.net/topic/124536-cbd-as-endocannabinoid-booster-of-t-cells/


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 18, 2021
Quote
most probably due to synthetic CBD

CBD and THC were provided by the National Institute on Drug Abuse (Bethesda, MD). All other reagents were obtained from Sigma (St. Louis, MO) unless otherwise noted.

We don't know for sure if it's synthetic or not, though we can't just denounce a study by throwing it under a rug due to the potential of it being synthetic.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
We don't know for sure if it's synthetic or not, though we can't just denounce a study by throwing it under a rug due to the potential of it being synthetic.

yes and thats why there should be poured millions in comparative studies as soon as possible, its word for immunization above all mids these pandemics, because waiting on the market to balance this will be slow and useless, on top in my opinion too many times was acknowledged that there are interest groups behind the studies skewing the true results eg. here is one elaborated example [1 (https://www.imdb.com/title/tt7444706/)] thus we will not see any real progress if there is not joint massive weighing of the effects of synthetic vs natural CBD ...
 


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 18, 2021
Before we discuss anything further, just want to let you know that I'm completely open-minded to any real scientific data. For example, I'm not a fan of the "moon-landing" or "global warming" -- I think both topics are politized nonsense. I'm not set in my ways like others in the scientific industry, so if you can convince me with hardwired evidence, I'm open to it.

Now, you think CBD can immunize against what exactly?

And, in reference to the video, what do you make of that?


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
haha about moon biases I am not insightful, but can point to global warming that is real, tho not as co2 but methane reflex [1 (https://historum.com/threads/threads/real-data-of-environmental-concern.188373/post-3432918)] ... about the proposed documentary about meat industry skewing studies data what to say find it on net You'll be surprised how corporatism is main democracy boss i.e. plutocracy [2 (https://www.politicsforum.org/forum/viewtopic.php?f=22&t=179924)] its almost same everywhere in the world, so hoping that we will see soon any positive change waiting per'se on not rarely corrupt institutions [2 (https://www.thenakedscientists.com/forum/index.php?topic=79357.msg633252#msg633252)] is almost wasted time, but with greater public pressure [3 (https://www.thenakedscientists.com/forum/index.php?topic=81962.msg633316#msg633316)] maybe things will change ...

about CBD immunization is enough that it triggers the lymph nodes production of T-Cells there is notion in the first post of scienticforums.net link, and in the last quoted study of the same CBD thread there is info of IgG antibodies uplift thus direct antivirus immunization is also in question, the only variable would be what quantity will be daily prevention dose of CBD, what as meme so I would share this info I've asked this question on bioforum maybe with hope that scientists will share this studies and at least debate on them maybe finally comparing the effects fro synthetic vs natural CBD ...




Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
I've missed somehow the link to bioforum ...

http://www.protocol-online.org/forums/topic/39351-amount-of-cbd-for-overall-immunization/


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 18, 2021
Quote
Knowing that CBD is T-Cell booster, I'll need assumption what amount of intake would be needed as daily "daily immunization"?

The only problem is that it is not. There's futility in this discussion because whatever data I provide, you'll end up telling me that the study was paid for by a corporation, that the government is controlled by the corrupt institutions, that the data is skewed due to x, y, z, etc. How do we begin to understand each other if your level of trust isn't there?

I've been part of this forum for a long time, and it's not my first time discussing topics with people that think like you. You'll end up just accepting anything that supports your hypothesis, while denouncing or rejecting all others -- that's not how science works. Science works because there's a consistency in evidence that branches out of every study. I linked a legitimate study earlier (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748879/) in this thread, yet your only criticism stems from anecdotal evidence that they used a synthetic form of CBD - how do you know? Assuming it is, how would a synthetic form of CBD, which shares 100% of the molecular qualities as the real thing, going to change the outcome?


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 18, 2021
You are projecting that I am like others and why because I've didnt analyze Your study but proposed variable that this could be due to synthetic cbd or eventual corporate skim, hm, as I remember I proposed positive studies on behalf of CBD as T-Cell booster in the links and your only answer was other studies say differently, then I said that should be weighed en'masse by the scientific community so we would be sure, which at the moment is not, but defacto just by google search You'll find extra amount of positive studies in comparison to scarcity of negative one on behalf of CBD benefits, stil I say thats not enough for me but we need to find why there are discrepancies in some and as answer to that proposed assumption that most probably is due to synthetic cbd!

  • above all eg. there are many reports on healed persons from carcinogenic illnesses with CBD still there is no study that I can find which points how, except the last one proposed in SF eforum thread linked above that mentions stimulation by CBD of the CD36 gene, thus I'll conclude there is big question Why there are so little funds allocated for en'masse studying of the CBD effects when such substance have even possible such potential , and only logical answer to this is corporate fear that is hijacking the governments on west from focusing extra on this research, not to go too much offtopic I'll just say mids capitalism is almost useless to expect big change in this field unless the masses dont wake up and put pressure to authorities to resolve this dilemma how so in most of the studies CBD is proved as beneficial and yet still the same is treated almost as alternative medicine, tho if You think that here we will weighed how big is that fact think we will end up just wasting time ...

... for start there should be one general scientific eForum for CBD where all this will be debated, also with parallel popular forum where layman like me will ask questions or volunteer for control group, simply we should see constant scientific debate on the matter instead just waiting on the governments to say whola now is the time for change, simply that will never happen mids plutocracy!


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 19, 2021
but defacto just by google search You'll find extra amount of positive studies in comparison to scarcity of negative one on behalf of CBD benefits, stil I say thats not enough for me but we need to find why there are discrepancies in some and as answer to that proposed assumption that most probably is due to synthetic cbd!

See, that's what bugs me, how can there be such a divide in scientific findings? Normally when you study something, the results are replicable, which is why all articles include a methods section in case someone in the future wanted to replicate the study. We assume that all published journal articles have been peer-reviewed, and hence have this credibility. If one study is showing that variable x is harmful, while another study is showing that it's beneficial, well then there's a problem. I understand that interpretations of results may vary, however. For example, researcher A may interpret results differently that research B, but the results shouldn't contradict one another unless the variables have changed.

Here's an article posted in Nature: https://www.nature.com/articles/s41598-021-81049-2.pdf?origin=ppub

Cannabis compounds exhibit anti‑infammatory activity in vitro in COVID‑19‑related infammation in lung epithelial cells and pro‑infammatory activity in macrophages

So CBD is an immune system modulator -- Great!

CD36 is an important scavenger receptor for phagocytosis of Streptococcus pneumoniae, a primary bacterial agent associated with pneumonia, which is down regulated by influenza.

Advantages and disadvantages of increasing macrophage phagocytosis activity should be carefully considered

Hence, we're not sure if this is even a good thing. Be mindful that these results were done in vitro, and extrapolation of any conclusions based on these results to in vivo situations requires that several points be kept in mind.

I'd appreciate if you stopped referencing other forums. I'm not going to scavenge other website threads for ideas and opinions when I can formulate my own. If you want me to review an article of interest, you're better off posting it here.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 19, 2021
Thanks for Your time Bio_Man ...

I'd appreciate if you stopped referencing other forums. I'm not going to scavenge other website threads for ideas and opinions when I can formulate my own. If you want me to review an article of interest, you're better off posting it here.

SiFo thread was posted so I can point to already selected few studies by me that points how CBD activates 2-AG and through it the lymph nodes to produce T-Cells, NaSci thread is just point that I am debating elsewhere on the matter tho where are thrown other notions like bioresonance or else, and the rest of the footnotes above were just attempt to point that indeed is strange how and why CBD is left on the margins altho has huge immunization potential ...

now whats the problem with me, I am simply layman, but eloquently furious why biologists are not debating nowhere in public on the matter, altho I've engaged sudently in this swirl while on SiFo I was bashed when said that CBD is natural alternative immunization mids this pandemics, and here I am now trying to hear opinions from others ...
 


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 20, 2021
Science isn't debatable; science is method and result. Your result is either correct or incorrect. Bioethicists are the one's that debate applications surrounding biological findings, weighing on the pros and cons of whether something should be used by society for the greater good. As a layman, are you well-versed on the immune system? Have you studied how immune system works, the cells involved in adaptive immunity? If so, enlighten us on how CBD promotes immunity towards COVID, and limit your explanation so that another layman could understand it. As Einstein put it: "If you can't explain it to a six year old, you don't understand it yourself."


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 20, 2021
I've already quoted studies in the SiFo thread where also pointed through links how lymph nodes work and how through CBD is activated 2-AG and through it T-Cells, think I dont need here again to relink all that!?

anyway my point for scientific CBD eforum is that there scientists should concentrate their studies debate and find out why there are discrepancies among few of them, it would be something like open debate by those directly involved in the experiments so people would see clearly where is the glitch and finally raise and put pressure on the governments not just why CBD is not free prescribed but why it cant be used as homegrown phytotherapy ...


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 20, 2021
I've already quoted studies in the SiFo thread where also pointed through links how lymph nodes work and how through CBD is activated 2-AG and through it T-Cells, think I dont need here again to relink all that!?

You should if you want to have a proper discussion on the matter.

There's a stigma behind marijuana that stems deep in every culture; this negative stereotype plays a part as to why many credible scientists don't want their names associated with. That, and the pharmaceutical industry cannot profit from naturally grown products because they aren't patentable. This leads to very few companies investing money into research


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 21, 2021
This leads to very few companies investing money into research

yes, and just imagine if it is cemented the notion that natural CBD is more effective due to complex balance of endocanabinoids in Cannabis Sativa [1 (https://www.thenakedscientists.com/forum/index.php?topic=81962.msg633762#msg633762)] then even less will be attractive for private funded studies ...

... maybe even worse plutocracy will invent gmo seeds that ruing the healing effect or introduce some wiping parasites so they would keep their big'pharma synthetic approach on legs, maybe I am exaggerating but until capitalism is norm these risks will be possible, in my opinion for the current elites selfsustainable masses independent from the system hook is unacceptable thing, I can just imagine how regular immunization with natural CBD remedy will make the current pharma and medicine fields in scarcity for consumers, sorry I cant imagine, but even 10% varriation will make all that system questionable how now works ...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 22, 2021
here is one interesting study in the quote of the next DTT post ...

https://defendingthetruth.com/threads/cannabis-edibles.127656/post-1661121

https://www.hanfanalytik.at/hanf/Welch-2014-Cold-Extraction-Method-For-Cannabinoids-THC-And-CBD.PDF


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Mar 22, 2021
Being able to extract CBD in its raw form is a relatively new technology; prior to that, every society perceived cannabis as a mind-altering drug. Therefore, it'll take at least 2 to 3 generations before cannabis oils become mainstream. For example, 50 years ago, canola oil (called rapeseed oil before) was an industrial chemical, used to lubricate engines or as lamp fuel. In its raw form, it tasted terrible and was bad for your health due to the erucic acid and glycosinolate in which it naturally contains. Once they learned how to remove these chemicals, they started selling it as CANola oil (Can stands for Canadian) and began marketing it as a healthy alternative to vegetable oil.

With all things considered, more research needs to be done with CBD. You mentioned that it can be used to boost the immune system, please provide the evidence. Show me your favorite peer reviewed journal article - the one that helped shape your pro-CBD opinion.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Mar 24, 2021
@bio_man first thing first, as edible is more useful check the next study, think if it would be compared in control groups with synthetic cbd the benefits will be more greater with natural raw intake, aside the chance not to depend on drug stores but own or neighbors plants ... check the quoted study in the next post ...

https://defendingthetruth.com/threads/cannabis-edibles.127656/post-1661121

hm, my personal opinion was shaped mostly by earlier personal experience in my life, but back then in '90s when I would talk with someone about the role of the endocannabinoid system in the body surely they would laugh, but things changed in this century and people started to open their eyes and search for studies, what for me earlier was done predominantly through NORML [1 (https://norml.org/blog/2010/07/01/theres-been-over-20000-studies-on-marijuana-what-is-it-that-scientists-do-not-yet-know/)][1 (https://norml.org/marijuana/library)][1 (https://norml.org/marijuana/library/marinol-vs-natural-cannabis/)]

now, as said I was insightful by experience and knowing little more about the effects of cbd, when this pandemics started so I would calm the fears I just connected the dots when through googling I've easily found that CBD stimulates the lymph nodes to produce T-Cells thus with little research on first site it could be seen that this goes through 2-AG ...

https://archive.is/L5Xer#selection-2505.1-2517.107

the rest is already provided as quoted studies on the SciFo thread where recently I've stumble on member ignorance on the provided studies as they were conspi assumptions instead scientific facts ... so I am not any special authority but can just wonder why there is such blackout altho there are many studies as You can see in the first footnote above from 2010 till then more than 20k, so raises naive question how much there should be before Marijuana is Legalized as home grown immunization remedy?

https://archive.ph/5zni2#selection-1443.2-1443.15

...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 19, 2023
I've missed somehow the link to bioforum ...

http://www.protocol-online.org/forums/topic/39351-amount-of-cbd-for-overall-immunization/

not that is extra important as is the next post, but here is archived link to BioFo thread ...

https://archive.is/DiSdg#selection-539.0-542.0

practically this is indeed issue what is the right prevention dose!?


Post Merge: 7 months ago

Think that the next one is and will be most precious medical info for whatever future turmoil in this World, simply gaining strong immunity by natural means mids global economic depression or after eventual fallout will be CBD relief for many ...

https://politicalhotwire.com/t/disposing-heavy-metals-from-the-body-cushioning-their-strike-after-nuclear-radiation.257007/post-8529986

... notion important for every next pandemic too!

https://defendingthetruth.com/t/cbd-vs-sars-cov-2.128559/post-1765498

Hm, what is interesting whether coz lucrative plutocratic lobbying or coz eventual malthusian fears of the elites I do find as compelling the witnessing of Andrew G Huff how the peer review process is skewed so would conform to the "institutional" narrative how there is not enough evidence CBD to be declared as Immunity T-Cell Booster what about to be invested public funds in its research!

 https://archive.is/T2XzP#selection-1825.161-1825.329


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 19, 2023
I totally forgot what our discussion was about here :lol: Mind catching me up to speed again?


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 19, 2023
@bio_man I've drop in to boost the thread with two important links to particular CBD studies and logic so would reemphasize how important substance it is as natural remedy [1 (https://archive.ph/N83Hp#selection-2310.17-2310.27)] tho it would be even more useful if others contribute too with useful ontopic studies ...


Title: Re: CBD as T-Cell booster studies
Post by: jcarter on Apr 20, 2023
I think CBD oils suffers from the bad reputation of the plant it is extracted from (that is, the cannabis plant). At one point in history, canola oil (derived from rapeseed) which is widely used today for cooking, was too bitter and toxic to use in culinary, but instead was a motor lubricant. Different varieties of rape were crossed to find plant strains low in erucic acid and glucosinolates. Years of research lead to the canola plants becoming indistinguishable in appearance from the related rape plants. The plant is now short, possessing branching stems, bluish green leaves, and yellow flowers. I think this sort of thing needs to happen with the cannabis plant if it has any chance of becoming a mainstream source of oil (be it for food or medicine). I've never smoked marijuana, but I have been around people that have, and they're a group that I generally don't like associating myself with.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 21, 2023
Reputation and Studies think cant be related in this case but in question is fear of the current profit'based'medicine that if People are boosting their organism regularly by CBD not just the profit but also whole current medical system will collapse, which even now is not selfsufficient what about if patient drop by magnitude!, aside that now there is extra large pool of volunteers for experimenting with chemical balance theory as response for longevity!


Title: Re: CBD as T-Cell booster studies
Post by: duddy on Apr 21, 2023
Scientific research in the United States on the effects of marijuana was limited in the early 20th, which is why we haven't done anything with it. The fact that it is natural has many powerful industries (the biggest being the pharmaceutical industry) motivated to provide the world with misinformation pertaining to its benefits. For example, they implement the idea that marijuana use can lead to addiction, mental illness, or other health problems, yet so can alcohol, painkillers, antidepressants, etc. Funny that those are allowed, but something that is grown from the earth is not. And it's not just big pharma that feels threatened by marijuana. The criminalization of marijuana  (in the USA) helped to protect the interests of the paper industry, which saw hemp as a competitor and lobbied to have it outlawed. Greed and money rules the elite, not the health and well-being of people.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 21, 2023
What is interesting is that the current model by which is legalized marijuana growth in usA is stimulating again criminals [1 (https://www.youtube.com/watch?v=jpNtnPzc7fU)][1 (https://www.youtube.com/watch?v=RUrfwJqpnpI)] instead to be introduced true motivation for all to have own plants its introduced commercialization, simply its too important issue to be left the market to be regulated by demand and supply logic, when and where the risks of misuse pile alone by itself eg. how who to guarantee that tomorrow what is sold has passed quality control or wasnt powdered by wrong chemicals, or wasnt even from start gmo'ed ~ aside that again those that are sick and depend from CBD could not afford to have it coz too sick to work or keep a job so would buy it from dispensaries ...

Practically how is now pushed decriminalization or legalization by stimulating wrong skunk approach that could be even lethal to teens [2 (https://www.youtube.com/watch?v=6U8XARojnbM)][2 (https://www.youtube.com/watch?v=PklZ_InpgPQ)][2 (https://www.youtube.com/watch?v=-JC0STLe-Ro)] like that actually is reestablished paranoia for quick as possible rollback of prohibition!, as if intentionally is chosen model that will push out again Marijuana as homegrown remedy and instead to be secured path for big'pharma'profit once again!?

Now can this be downregulated to level of homegrown legalization dont know, having normal full legalized homegrown for all mids cities is temptation for the Youth so it could be introduced some cleaver bargain eg. urban citizen can have it as investment in some rural coop if dont have will to move rurally where would be allowed free for all planting of such health beneficial plant, ideally such co-op's should be state-private partnership so would be secured quality and price somehow, instead like now everything to be left to the market on neoliberal capitalist juggling mostly stimulating dependence from legal if not illegal dopeman at the end of the street instead the herb to be demystified so would collapse its current idolization as dope and it would skyrocket its CBD importance as homegrown remedy ...
 
Post Merge: 7 months ago

And it's not just big pharma that feels threatened by marijuana

Seen from eventual malthusian fears of euroatlantic determinists as western eugenic elites, think wide use of CBD by the masses is greater treat for "them" than eventual fears of big'pharma, and altho looks like profit is prime motor behind the scene in my opinion ideology is far greater so to speak if the useless eaters are healthy and long living "someone" could not reach easily "its" utopian superhumanity and heaven'on'earth!, I've thrown similar logic elswhere too ...

https://biology-forums.com/index.php?topic=2054205.msg5413740#msg5413740


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 22, 2023
Many of the concerns mentioned in this video https://www.youtube.com/watch?v=-JC0STLe-Ro are legitimate. For example, marijuana infused candy is something that can easily be misinterpreted by a child as safe, leading to a potentially dangerous situation. These "edibles" have a high percentage of THC, which as pointed out is addictive. Thus, whether or not the legalization of marijuana may decimate the profits of the pharmaceutical industry by offering a natural way to reduce pain, ease anxiety, etc., it still needs to be heavily regulated for the overall safety of the population. Left unchecked, it will only impact those that are most venerable, namely teenagers and young adults, whose brains haven't yet fully developed.

@Odiseizam: You can use the code [nobbc]link[/nobbc] around YouTube links to prevent them from turning into videos


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 22, 2023
If You ask me thats why we need rural legalization and eventually rural co-op's managed by the state where would be grown large amount of weed that will be then by controlled quality and price deliver to door for every registered consumer or citizen investor that had participated with own plants in the co-op ...

Stil teens will have always ways how to circumvent the system and the black market will be yet again active if not else for them, what should be tackled by hype for sport lifestyle, yet again public anti-skunk campaigns should be also norm as are anti-smoking one, but basically the problem is that is gateway relaxant that by default is bringing the dope hype to many Souls and that cant be anyhow tackled but by spiritual warnings that even Marijuana what about legal or illegal drugs are harming the Nous (the noetic eye of the Soul) [1 (https://forum.gizadeathstar.com/t/xylazine-is-new-drug-sweeping-the-nation-and-coming-soon-to-the-pacific-northwest/11074/48)] i.e. its open door for empowering by spirits what could be even more dangerous than physical addiction as side effect (altho its mutual process as I am aware coz what secures the addiction are demons-anathema-to-them but go explain this to MD's that are stick in reductionist humanist mindset i.e. to advise patients to focus on healing by Grace)

Yet even when the Soul is cleansed by Inchurched Consecrated Life, it could still exist behavioral reflex like habit to have something in hand while hanging with the friends, thus it could be again tempting someone to relapse till in my opinion dont substitute that habit with other more effective what in case of smoking is by default some sport activity, even it was table tennis from time to time [2 (https://defendingthetruth.com/t/ways-to-quit-smoking.127500/post-1648956)]


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 23, 2023
I'm not sure if Hollywood's depiction of stoners is true or not, but I don't like the crowd associated with regular weed smokers. They usually elevate the substance to godhood, worshipping it as if it's God's most prized gift to man. Potheads are seen as lazy, unproductive, and they all have this false sense of rationality of which is extremely annoying to me. Furthermore, most heavy users don't pursue a lifestyle that revolves around hard work and perseverance - the same argument can be used for alcoholics (in fact they're even worse). Given what you know about the benefits of marijuana, would you encourage your own children to use it? If the answer is yes, then you know what side you're on...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 23, 2023
Think we are going too offtopic if we continue with the risks tied to the recreational use of Marijuana, but even then we need to differ skunk as thc concentrate with natural Marijuana, think the bbc docu segment [1 (https://archive.ph/PKTMM#selection-1131.8-1181.6)] hits the nail around the difference, now would prohibition stop the junky hype hm probably not but education and investment in healthy sport trends it will!, the question is how that to be achieved what think is doable if eg. gambling as vice is only state allowed sector from where all money would slip in sport for Youth, think Nederland is good example for this, but again it depends on the model the mentality the perspectives, how and why to expect that mids ghetto and no future ahead the kids would prefer normal lifestyle its logical will get high so would escape its misery of dull and poor reality dependent either on welfare or crime!, the problem now is that this is not only case mids the commieblocks but mids the suburbia too thus go find good demotivation for street'life'style trends, hm maybe as I've said with rural legalization for personal growing many could move on country and with bit machinery ring help alike incentives to be stimulated on farming selfsufficiency altho again that will not resolve the issue with the emptiness in the atheist hearths that nor have fear from Authority from Above nor see Afterlife as possibility and chance so would focus to escape hedonistic trap for "I want it all I want it now" what as always was indulgence in sex&drugs&alcohol almost in every epoch but now when we are for quite some time brainstormed by secularism it became pademic of decadence that actually is stimulated since the introduction of the fiat system and the need trough consumerism to be chased economic growth!, thus per'se simple prohibition or extra legalization will not resolve the risks of the current trends, but to overseen the benefits of having own homegrown remedy that regularly would be used as CBD condiment for extra immunization that is think more than wrong!, hm we can open new thread if You like to address these issues, here in this thread think its better to debate the proposed studies about CBD as T-Cell Booster ,,,


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 23, 2023
Staying on topic, here's a pretty good review...

Key takeaway:

Considering all the studies conducted on immune responses and inflammation, the data overwhelmingly demonstrate that CBD is immune suppressive and anti-inflammatory (Fig. 1).


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 24, 2023
Hm bio_man it would be ontopic if there was suggested some CBD to T-Cell Study, while suggesting like this anti-cbd review as summary by one of the elite peer'review'journal bands plus excited by genetic'medicine'hype [1 (https://archive.is/r56eF#selection-483.0-483.433)][1 (https://archive.is/xNNys#selection-1757.0-1773.9)] so this sounds to me not even like digression but spamming (dont take it personal) :) especially now when I've recently learnt how rigged is the peer'review'process [2 (https://archive.is/YwRmG#selection-6447.86-6447.140)][2 (https://archive.ph/N83Hp#selection-2387.114-2393.52)] thus logically paid propaganda by the pharmaceutical lobby that in its next steps of lobbying would use such arguments for federal legislation in usA probably [3 (https://archive.ph/9Vbw5)][3 (https://archive.is/KKWyL#selection-2345.356-2345.388)]

Anyway I am glad You've posted such general review so would point again how easily can be manipulated the public around the effects on immunity where is not stated whether the mentioned bad side effects are from studies due to CBD derived synthetically or from natural plants, what think needs to be finally resolved what eventually will provoke also interest in bioresonance [4 (https://archive.is/CmZJE#selection-4679.16-4679.47)][4 (https://archive.is/JHUdt#selection-2915.0-2923.224)] but above all will force many to have own plants instead waiting on others to deliver them this natural booster of Immunity ...

... also more importantly this could open strange hype for questioning of the synthetic biochemistry ~ if this issue with the effectiveness of artificial and natural substance is addressed persistently ~ what think will result with reevaluating of all generic pharmacology and give emphasis on phytotherapy instead chemical mimicry of healing with the current drugs and vitamins! 


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 24, 2023
Hm bio_man it would be ontopic if there was suggested some CBD to T-Cell Study, while suggesting like this anti-cbd review as summary by one of the elite peer'review'journal bands plus excited by genetic'medicine'hype [1][1] so this sounds to me not even like digression but spamming (dont take it personal) especially now when I've recently learnt how rigged is the peer'review'process [2][2] thus logically paid propaganda by the pharmaceutical lobby that in its next steps of lobbying would use such arguments for federal legislation in usA probably [3][3]

Yikes, I just realized it's from "Cannabis and Cannabinoid Research", that's a major blunder from me, sorry! I'll try to find a better one...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 24, 2023
The seriousness of the impact to the current big'pharma and profit'medicine that could have CBD if it is elevated as acknowledged Immunity Booster is far greater than the need and means to corrupt eg. at least the editor of that journal (journal that belong as I've pointed to band that per'se gives greatest accent to genetic medicine!), aside that the editor also has conflict of interests [1 (https://archive.is/QjwsR#selection-1229.0-1229.43)][1 (https://archive.is/SoQuf#selection-741.0-743.22)] simply if we want to be taken anyhow seriously the peer'review'process after the witnessing of dr. Andrew G Huff (the 2nd footnotes in my previous post) then defacto the same should be "nationalized" and given to the academia exclusively, altho that would not be complete safety from corruption thus it needs to be introduced and eTOS environment where any review will be open to full eforum debate among experts thus challenged the reviewers too, ideally for every study there should be mandatory eforum if it was funded by state money ...


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Apr 24, 2023
#1

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells

Clinical studies have confirmed that CBD reduces the levels of pro-inflammatory cytokines, inhibits T cell proliferation, induces T cell apoptosis and reduces migration and adhesion of immune cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669958/pdf/APHA-214-63.pdf

#2

Antioxidative and Anti-Inflammatory Properties of Cannabidiol

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023045/#B66-antioxidants-09-00021

#3

Cannabinoids as novel anti-inflammatory drugs

Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/pdf/nihms155268.pdf

* Mind you, none of these sources are financially affiliated to the marijuana industry. 


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 24, 2023
Thank for Your time and will to contribute the thread ... yet in #1 we can read in the abstract "This review summarizes the chemical and biological effects of CBD and its natural and synthetic derivatives" [1 (https://archive.is/DJHQu#selection-1005.13-1005.46)] also in #2 we can see in references that its sum from synthetic cbd too [2 (https://archive.is/LrMke#selection-6827.2-6831.2)][2 (https://archive.is/LrMke#selection-5567.56-5567.99)][2 (https://archive.is/LrMke#selection-6445.2-6449.2)] and finally in #3 also 15 times pointed that s-cbd is used as measure, thus I'll take again the freedom to point that Natural CBD extract has completely different effects than the artificial ... check the studies from the SiFo thread in the first post of this one ...

... practically till this issue is not addressed adequately by the science it will be misused as I suspect as by big'pharma so as by profit'medicine so would be derailed attention of CBD as natural immunity booster and again given emphasis on vaccination as ultimate solution altho fallacy parexcellence if we have in mind that virology is in vacuum!, simply its too big to fail skim in my opinion the chase for superhumanity that is flushed by vaccination as gateway for bionic&genetic revolution so now would be thrown lid by CBD as immunity booster and removing the progress driven by fear pandemic and jabs coercion!, at least this is my conclusion and if You prefer to accept "their" hype it Your free will altho sad choice how many actually are willing to become experimental group for still not fully understood virus theory science and response at best ...

https://biology-forums.com/index.php?topic=2054205.msg5414315#msg5414315 (https://archive.is/2B1V7#selection-7723.0-7723.121)






Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 25, 2023
Here is interesting conclusion derived from the two footnoted studies, somewhere before the legalization and commercialization of Marijuana in usA, studies where the accent is not so much on Lymphocytes as on the Thymus (as postprocessing plant for lymphocytes) obviously confirming that the correlation is logical, yet again I would like to see verification by researchers ideally offering comparing results from natural and artificial CBD ...

Quote
Both CBD [1 (https://pubmed.ncbi.nlm.nih.gov/18387516/)] and THC [2 (https://pubmed.ncbi.nlm.nih.gov/12130702/)] have been shown to cause cancer cell death (apoptosis) in those with thymus cancer. However, these are lab tests, and more research is needed into cannabis’s efficacy for thymus cancer in the real world.
...
The thymus is located in the upper front part of the chest, and it is the primary lymphoid organ of the immune system. It is an extremely important organ that helps lymphocytes (T-cells) to mature. Cancer of the thymus is a relatively rare cancer, occurring in about 1.5 people for every million people in the US every year. Survival rates for localized or regional cancer of the thymus is quite high – around an 80% or 90% 5 year plus survival rate. If it spreads further, the survival rate drops down to 40%.
[3 (https://leafwell.com/medical-conditions/cancer-of-the-thymus/)]

... anyway I still cant find dedicated Team if not Institution that tackles specifically CBD as T-Cell Booster!, tho probably there are some, but still knowing how in The Journal of Immunology (in redaction of The American Association of Immunologists) there are published just 54 studies since 1979 I dont see hope that we will see quick paradigm shift [4 (https://archive.is/IJsBC#selection-1451.45-1453.4)] altho recently mids the past pandemic there were academic groups that I'll say accidentally jump out in public, still as they've appeared instantly even more instantly were forgotten by the media [5 (https://defendingthetruth.com/t/cbd-vs-sars-cov-2.128559/post-1765498)]~[5 (https://archive.is/eigxG)]~[5 (https://defendingthetruth.com/t/alkaline-lifestyle-vs-mrna-vaccines.127393/post-1679708)][5 (https://web.archive.org/web/20210928104551/https://www.youtube.com/watch?v=g9-gv9ayUpI)] simply the emphasis is on vaxing as immunization and thats it!, also I am not sure how much state and private funds are directed towards CBD Immunity research eg. in comparison with other immunity boosting studies, yep it would be interesting to be seen such research investment chart, on what we can confirm or dismiss the assumption that there is intentional suppression of such research and studies by the current med&pharma elites further secured by peer'review'cauldron and regulatory bodies!

And until this is not case. instead to be elevated the benefit of CBD think it will be peddled the idolization of THC, altho as I've already pointed what is harmful noetic hype that instead to be healing on contrary like skunk (earlier hashish overindulgence alike trance) is provoking people to be easy pray for demons-anathema-to-them!, what actually was as always case yet many still cant grasp the true risks from such skunk trend which is maybe not on level of jimson weed possession but how much evil is enough evil!?, how much is enough for someone to be open for spiritual attacks - which tho for many are seen as inspiration from muse (or chillout stoners well) altho defacto an opened door for spiritual parasites, I mean when tobacco smoking is such momentum how much more when the smoke is psychoactive!?, one need just to that to add some spiritual praxis and to drop even further down the drain!, what actually was norm for and in many occult groups [6 (http://www.politicsforum.org/forum/viewtopic.php?p=15200222#p15200222)][6 (https://academic.oup.com/book/32526/chapter-abstract/270273716?redirectedFrom=fulltext)][6 (https://forum.gizadeathstar.com/t/xylazine-is-new-drug-sweeping-the-nation-and-coming-soon-to-the-pacific-northwest/11074/48)] what somehow nowadays again is stimulated how through commercialization is legalized Marijuana and left on the market to offer ultrahigh thc concentrates claiming how that is healing or normal pain killer, hm maybe as such useful for those who are hooked on opiates or benzos, but for fun such trend to be norm cmon, the risks from such inertia will bring if not else dullness if not apathy for many what eventually will pull them on springboard to heavy drugs coz tolerance due to overindulgence with high potent weed!, So on one hand we need to search useful models of Legalization on other demystification of the healing properties of CBD, but what will not become case up until we dont see constant debate on dedicated political and expert eforums so would be reached clarity if not consensus what should be secured right after on referendums ... to be more ridiculous looks like that CBD would become trend for Pets [7 (https://www.annualreviews.org/doi/pdf/10.1146/annurev-animal-081122-070236)] while for us will be some expensive alternative extract that as with all the foods&remedies it would be more convenient to be reached as artificial substitution, Luckily There Are Studies That Are Accenting The Negative Effects Of synthetic cbd, but Hm I do expect if things get on the right track (by "someone") to be introduced wrong gmo'ed seeds that will corrupt the natural weed, So my advice would be in time gather natural cultivated or wild seeds ...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 26, 2023
Here is some interesting review that is addressing somehow maybe more clear the elusive pitch in the studies that CBD is indeed effective yet with negative potential too > an paradox that needs to be resolved fastest as possible so would not be misused by big'pharma for bashing of CBD as immunoboosting remedy ~ what again think is result due to the synthetic cbd studies!!! ~ also as commercial summary it dont gives exact direction from which studies derived the conclusions ...

https://www.phytopluscbd.com/blog/how-does-cbd-affect-the-immune-system-and-autoimmune-diseases (https://archive.is/qH81n#selection-1469.0-1476.0)

... I'll reassert my point that as natural extract (if we are speaking also about natural non-gmo strains of CS) its illogical to have negative effects on the immunity, yet again I will not claim blind certainty and Hope this will be vastly researched and confirmed as are many MDs and Scientists pointing that they see and recognize the positive effects but want more research, hm but how much will be enough before we see wide acceptance (by the current obviously heavily biased by big'pharma academia) of CBD as immunity booster, here is one example prof.dr. Reuven Or (former director Department of Bone Marrow Transplantation and Cancer Immunotherapy, Baxter Hadassah Research Center, Jerusalem) who even half decade ago acknowledges the unique potential of CBD altho as guest on canntech conference it could be also seen as biased suggestion of speech [1 (https://archive.is/KInqw#selection-3869.11-3925.11)] yet gives another perspective that its question whether will be further explored how underfunded is CS research!?, and if and when that will be case except differng of studying natural and artificial CBD probably greater accent will need to be given on the issue of dosage or how all receptors behave as ECS and phytocannabinoids so would be achieved desired immunoboosting effect ~ about what I've found only one interesting line from abstrac of some research compeling to this assumption [2 (https://archive.is/GxnPT#selection-449.468-449.705)] that hm could give maybe direction towards mastering hematopoiesis with phytocannabidoids [3 (https://archive.ph/CyKwW)] what also half decade ago is mentioned by the antifauci antiplandemix fighter [... (https://politicalhotwire.com/t/mrna-vaccine-risks.241340/post-8203483)] the virologist dr. Judy Mikovits (founder of M.A.R.C. INC and director of Cancer Biology at EpiGenX) in ontopic webinar where she is examining some study about THC as modulator of Hematopoietic Stem Cells (HSC) [4 (https://archive.ph/1FzE1#selection-2473.31-2655.14)]~[4 (https://pubmed.ncbi.nlm.nih.gov/33331878/)] overall this is completely different issue altho defacto potential high natural healing idea but instead about proliferation of Lymphocytes about boosting of the Stem Cells ~ for what probably we would need different thread ... anyway think this examination of dr. JudyM should be regular occurrence as vlogs and blogs of insiders in ECS and Immunology ~ ideally joined in some ontopic thematic eforum so would be raised the attention of the academia and like that to be mobilized as much as possible Researchers on the matter ...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 28, 2023
... pardon she is not virologist but molecular biologist ... now not that I am some antivirology buff, altho do have almost assurance that indeed there is some old eugenic spin (that coz particular superhumanity lusts) laid path to be seen viruses as invader organism [1 (https://biology-forums.com/index.php?topic=2054205.0)] so cant say how adequate for this thread is the next footnoted addressing of dr. JudyM about the plague of corruption (around plandemix and m'rna vaxing) simply she worked and see virology as true science theory, yet aside her earlier career with nihs fauci&co, Still think she has ultra appealing point about CBD as Alternative Immunization  [2 (https://www.spreaker.com/user/cannabis/the-real-threat-of-covid-19-and-how-cann)][2 (https://web.archive.org/web/20220929053331/https://thecannabisreporter.com/the-real-threat-covid-19-how-cannabis-can-help-dr-judy-mikovits/)]~[2 (https://archive.ph/GafCI)][2 (https://archive.ph/XTuOv)][2 (https://archive.ph/ryZs0)][2 (https://archive.ph/ql5bA)] what was further expanded as presentation on cannaexpo in 2020 [3 (https://www.brighteon.com/c3208e78-e787-443e-9ef3-3289eb954d38)] as short useful info like direction for exploring (the interferon connection is also refreshing info) …

In the next tagged video in ~10th min there is also very unique claim about ECS as basic door for Stem Cells [4 (https://archive.is/VLbzx#selection-1879.24-1963.34)] … also in the second interview for the same radioshow (hosted by dr. Michael Karlfeldt on HealthMadeRadio) dr. JudyM is pointing to another interesting claim about retroviruses [5 (https://archive.ph/INwAr#selection-2859.23-2991.14)] so in essence we have issue with deficiency of own endocannabinoids in our bodies thus phytocannabinoids come as most needed substitute so would be restored Immunity ... So Make CBD Smoothie or Dressing an Regular Condiment in Your Daily Diet especially if have health issues or need to keep Your Organism Young …  

https://www.youtube.com/watch?v=6ATPhysqazM&t=491s


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Apr 30, 2023
Wow how they measured the viral particles if indeed viruses cant be observed [1 (https://biology-forums.com/index.php?topic=2054205.msg5414400#msg5414400)] is there maybe some dna virion catcher!?, hm still cant accept that we were all fooled to follow germ theory for whole century, is it really possible such error to accepted promoted defended and imposed as mainstream norm!?

Anyway the point from the next vlogged study is that CBD "effectively eradicated viral RNA expression in the host cells I mean wow they weren't getting the viral expression the virus just couldn't reproduce inside those cells" [2 (https://archive.ph/SINoO#selection-2943.0-2997.37)] hm could it be that if studies burst enmasse that "they" could not rig or skew the peer'review'process!?, or good cop bad cop will be now played till tilt away the masses with gmo CS seeds, hm wonder whether already the wild strains are not mutating due to the commercialization of Marijuana and as result the "silent" plunge of gmo'ed strains!?

https://www.youtube.com/watch?v=Bz4fn2QFO_A


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 8, 2023
I became aware that CBD plays beneficial role in artherosclerosis as prevention [1 (https://defendingthetruth.com/t/cbd-vs-sars-cov-2.128559/post-1731053)] tho now as I can see it can directly and indirectly affect blood vessel recovery, directly as explained by the tagged video below (here is transcript too [2 (https://youtubetranscript.com/?v=ZJoaabS3Qz0)]) while indirectly as booster of T-Cells coz as could be seen from the first tagged url bellow (play huge if not main) role in healing of wounds, thus boosting T-Cells by CBD can be more than useful in treating wounds ... probably it should be seen how will act as oil beneath hydrofiber dressing or as addition in other wound treatments [3 (http://www.build.mk/forum/forum_posts.asp?TID=1487&PID=138654#138654)][3 (http://www.build.mk/forum/forum_posts.asp?TID=1487&PID=169071#169071)] and if this is indeed effective fast cardiovascular healing of wounds then CBD Oil should become regular surgery treatment before closing ...

https://www.liebertpub.com/doi/10.1089/wound.2021.0059 (https://archive.is/BKsI1#selection-1899.84-1913.223) ~ The Role of T Lymphocytes in Cutaneous Scarring
~ Walker D. Short, Xinyi Wang, and Sundeep G. Keswani

https://www.youtube.com/watch?v=ZJoaabS3Qz0


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 13, 2023
Think that for now this thread is enough filled with supporting studies or logic about the ultrabeneficial effects of CBD ... still there are conflicting study results, where intentionally or not, just like in the next review, its not just negated its immunity effects but even bashed as counter-effective, yet dont need to wonder why!, thus I'll shout out again that we must put extra effort in demystification when and how CBD can went rogue, in my opinion if and when its produced synthetically!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877666/ (https://archive.is/PgVSY#selection-3126.0-3126.1)

Hm, wonder how should I keep my eyes wide shut in context of the eU regulation for CBD remedies to be "restricted from being marketed as medical products improving health" [1 (https://www.ingentaconnect.com/content/govi/pharmaz/2020/00000075/00000010/art00002;jsessionid=1hq4c6qpvgnj0.x-ic-live-03)][1 (https://wonnda.com/magazine/sourcing-cbd-products-in-europe/)]
 


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on May 13, 2023
Looking at this from a different perspective for a moment, why the sudden fascination of this plant in discovering any of its medicinal properties? I mean, why are organizations spending millions of dollars to discover how this plant interacts with the immune system? Why not use another plant, such as mint or dandelion? Could it be that all plants, studied at this level, have the same effects, but aren't studies enough to achieve any conclusions? I think there is something sinister about this sudden fascination by scientists in their interest in cannabis.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 14, 2023
Not all plant engage with the ECSystem, while Cannabis Sativa has abundance of CBD that did but also grows invasively like weed, tho there are other Plant that can serve the purpose yet the CaSa is far more cost effective ...

https://www.fundacion-canna.es/en/traditional-plants-engage-endocannabinoid-system-and-their-medicinal-potential (https://archive.is/lzzRV#selection-646.0-646.1)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931553/ (https://archive.is/agmhS#selection-2773.0-2777.9)

https://aor.ca/wp-content/uploads/uploads-large/AOR%20-%20Advances%20Magazine%20-%20Vol%206%20Iss%201%20-%20CAN%20-%20Digital.pdf (https://archive.is/LI30H#selection-1107.0-1149.11)

So its hard anyone to claim anyhow any conspiracy, unless there is some beyond our understanding spiritual spin so as plant would be idolized and like that altho unique remedy in the end to become wrong temptation!?, but such metaphysics cant known to us!
Post Merge: 6 months ago

Sorry for the typos, but yesterday I've noticed in another post some system hickup in that case about the repeating quotes [1 (https://biology-forums.com/index.php?topic=2054880.msg5416586#msg5416586)] tho coz havent noticed and edited the post in time here is correct repost (bellow), not that matters but like this will emphasize the importance of the conspy notion coz indeed many cant grasp the risks from addiction to THC especially skunk as high potency thc strains which (ab)use is on level of heavy drugs, altho even those can be useful as substitution for benzos but if prescribed as natural painkiller, still knowing that just recently masses are becoming aware of the risks for "psychosis" from skunk (I'll say paranoia and dulleness per'se) its good to be used every opportunity to point this and forward people to use CBD Extracts as immunity booster, altho still not all can afford such remedy, thus using natural wild hemp leaf smoothy or Natural Marijuana buds as regular spice for cooking can come handy, tho think that as phytocannabinoids are wasted abundantly when treated thermally, its same with smoking hm even worst from soteriological perspective if we know that smoking is sinful habit, So Eat The Weed when You'll decide to boost Your Immunity with CBD ...

~

Pepost x2


Not all plants engage with the ECSystem, while Cannabis Sativa has abundance of CBD that did, but also grows invasively like weed, tho there are other Plants that can serve the purpose yet the CaSa is far more cost effective ...

https://www.fundacion-canna.es/en/traditional-plants-engage-endocannabinoid-system-and-their-medicinal-potential (https://archive.is/lzzRV#selection-646.0-646.1)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931553/ (https://archive.is/agmhS#selection-2773.0-2777.9)

https://aor.ca/wp-content/uploads/uploads-large/AOR%20-%20Advances%20Magazine%20-%20Vol%206%20Iss%201%20-%20CAN%20-%20Digital.pdf (https://archive.is/LI30H#selection-1107.0-1149.11)

So its hard anyone to claim anyhow any conspiracy, unless there is some beyond our understanding spiritual spin eg. so as plant coz the intoxicating THC would be idolized and like that altho unique remedy in the end to become wrong temptation!?, but such metaphysics its not known to us! 


Title: Re: CBD as T-Cell booster studies
Post by: duddy on May 15, 2023
Agreed ^^ There's no conspiracy behind a plant whose history can be traced back thousands of years. The earliest recorded evidence of marijuana use dates back to around 500 BCE in Central Asia and China! The Chinese were among the first to document the medicinal properties of cannabis. The plant's fibers were also used for making textiles and rope, so it has significant cross-cultural importance


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 21, 2023
so it has significant cross-cultural importance

It would have even greater if Natural CBD is recognized as regular immunological remedy ... also that will collapse the hype around Marijuana as recreational light drug, altho has own risks to provoke tobacco alike trend if its not suppressed advertising, and probably will ask even greater emphasis on sport and healthy lifestyle as mandatory trend at least in schools [1 (https://archive.is/xDaGY#selection-8497.67-8497.261)] for what ideally it would be good for poor countries to nationalize betting and gambling and all profit to be directed in Free Sport for Youth what effectively will remove it as wide spread temptation ...

... also having relaxant for laugh instead chemical antidepressants will cushion many wrong addictions in elderly, still those high thc strains and dosage should prescribed only for extra ill ...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 25, 2023
things changed in this century and people started to open their eyes and search for studies, what for me earlier was done predominantly through NORML [1 (https://archive.is/HY4eU)][1 (https://archive.is/XCZpj)][1 (https://archive.is/twhSP)]

wow I was expecting that state funding of CBD research exploded in usA but obviously its still kept under the rug!, why hm think dont need to repeat!?, yet its strange just few studies to pass altho utmost important chance for T-Cell boosting by CBD, altho since 2011 on NCI page clearly is pointed effective cancer apoptosis (cell death mechanism) [1 (https://archive.is/KddBM#selection-1605.0-1613.93)] but this fact got buried not just invitro by using ineffective or countereffective synthetic cbd but also invitro too [2 (https://archive.is/srvRb#selection-6425.3-6425.74)][2 (https://archive.is/LaAdb#selection-591.0-591.42)] so what else to say that it smells on eugenic spirit behind "the" curtain ~ probably "they" think to themselves as eugenic determinists "whats the logic to keep ill alive if didnt deserved" and most probably even more afraid all the useless eaters especially as poor to keep living!?, hm Sorry for this sarcastic antielitist slap but how else to be explained the next ridiculous statistic of state funded studies as listed on NCI where logically most of the ill would search for direction [3 (http://)][3 (https://archive.is/OsOvZ#selection-4439.23-4441.1)] tho elsewhere could be found bit more yet still ridiculous [3 (https://archive.is/0YKEj)][3 (https://archive.is/234FH#selection-2448.0-2450.1)] (guess most of them with synthetic cbd), and on top when searching what cancer.gov has from studies on CBD there is endless loading on the page, probably not intentional glitch tho adds to the frustration of unbelief how indifferent is usA about potential immunity elixir while in same time do fund by billions wrong experimental biotech!

So for terminally ill is more like diy treatment, what kudos to dr. prof. dr. Patricia Crone is shared as own experience in the docu For the Life of Me: Between Science and the Law [4 (https://archive.is/gdzXG#selection-1557.23-1611.23)][4 (https://youtu.be/va1ElZfr6Hk?t=133)][4 (https://www.imdb.com/title/tt4687716/)] and altho she was given just 2 years with chemo she refused it and as could be seen on own hand got 10 more years life ... altho I'll not recommend going on own hand coz now there are plenty CBD to be bought as extract even MDs can recommend dosage thus not need to walk her diy especially knowing that like that You'll end up with large doses of thc in the head what as could be seen from the previously posted bbc docu 3rd clip in post #25 6 (https://biology-forums.com/index.php?topic=1975202.msg5413738#msg5413738) is not some pleasant experience, so in my opinion go after extract of CBD that has no intoxicating side effects!, yet what to do healthy individuals who are aware about CBD benefit to their immunity but dont have money to use it regularly as prevention, for them again I'll say go harvest wild hemp leafs make smoothies and stuck up Your fridge [7 (https://defendingthetruth.com/t/cannabis-edibles.127656/page-2#post-1661121)] be clever infuse it in honey so would use it regularly ... and dont forget that stress decimate the immunity on half so You make some effort to smile regularly!


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on May 25, 2023
Quote
It would have even greater if Natural CBD is recognized as regular immunological remedy ... also that will collapse the hype around Marijuana as recreational light drug, altho has own risks to provoke tobacco alike trend if its not suppressed advertising, and probably will ask even greater emphasis on sport and healthy lifestyle as mandatory trend at least in schools [1] for what ideally it would be good for poor countries to nationalize betting and gambling and all profit to be directed in Free Sport for Youth what effectively will remove it as wide spread temptation ...

Interesting point made here. In the early days of Coca-Cola's development in the late 19th century, the original recipe did indeed include cocaine as an ingredient. The stuff was originally marketed and sold as a medicinal beverage. By the early 20th century, Coca-Cola had fully transitioned into a non-medicinal beverage and focused on its status as a refreshing soda. Perhaps, if this were true for Coca-cola, then it is also possible for marijuana industry?

New ideas take generations before they become mainstream; if these ideas were introduced today, it would likely take half a life-time (maybe?) before you see it come to fruition. As the moment, most countries have banned marijuana, so it is an uphill battle. Societal attitudes and perceptions take time to change, it starts by introducing an idea to the younger generations first; once they grow up and are allowed to vote, then the real change occurs. Bottom line is that it is possible, but takes time...


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 26, 2023
Some interesting coincidence was that just right before the s'c'2 hype of pandemics Corona Beer through its parent company Modelo was preparing to release CBD infused beverage [1 (https://youtu.be/vyCtDi-znOM)] what a misfortune or maybe some metaphysical ethereal association strangely like good hint, or maybe arranged conspiratively as bad psyop  like appeal to fear spin, hm dont mind mine out of box mosaic reasoning that nothing is accidental tho probably wrong in this case, still took the liberty so would provoke attention grab in own agitprop style ...

... anyway defacto CBD should be part of every beverage but natural one and not synthetic substitute, otherwise instead immunity elixir it will become wide health hazard!

About eventual paradigm shift hm having in mind the hedonistic treadmill theory such slow pace has no logic, especially not if we know that CBD is already recognized sold and marketed as beneficial medical substance (tho still not praised about its T-Cell boosting potential) but that will not stop the food&beverage market to use it as ingredient the problem tho is that still there is no wide agreement around the dosage ... practically when I say in the previous post diy improvisation this stands even more especially coz many homecooks cant separate CBD efficiently or cheaply thus make cbd thc tincture and that again is stress to the organism coz the intoxicating nature of thc that in such tinctures is concentrated in excessive amounts!, thus be smart and find steady supplier of CBD extracts, or invest in own industrial hemp fields and some cbd extraction knowhow [2 (https://cedarstoneindustry.com/the-difference-between-supercritical-co2-and-ethanol-extraction/)][3 (https://forum.grasscity.com/threads/cbd-vs-covid19.1597195/#post-25749237)][3 (https://archive.is/Fl6pe#selection-5551.0-5569.23)][3 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290527/)][3 (https://defendingthetruth.com/t/cannabis-edibles.127656/post-1661121)]
 


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on May 26, 2023
Quote
About eventual paradigm shift hm having in mind the hedonistic treadmill theory such slow pace has no logic, especially not if we know that CBD is already recognized sold and marketed as beneficial medical substance (tho still not praised about its T-Cell boosting potential) but that will not stop the food&beverage market to use it as ingredient the problem tho is that still there is no wide agreement around the dosage ... practically when I say in the previous post diy improvisation this stands even more especially coz many homecooks cant separate CBD efficiently or cheaply thus make cbd thc tincture and that again is stress to the organism coz the intoxicating nature of thc that in such tinctures is concentrated in excessive amounts!, thus be smart and find steady supplier of CBD extracts, or invest in own industrial hemp fields and some cbd extraction knowhow [2][3][3][3][3]

The issue is conflicting studying suggesting both good effects of CBD and bad effects. It's not a win-win situation to implement CBD yet, as public perception, especially in the USA is still not mainstream. Look what happened to Bud Light, one stupid move lead to now months of bad sales. They thought the public was fully accepting of these current trends, but the silent majority woke up in a roar against the company. And rightfully so, since they did not do their market research properly. That's precisely what I think would happen to Corona beer too. Moral of the story is that if you're in charge of a multi-billion dollar company, you don't just cross your fingers hoping something will catch, especially when it deals with sexuality. Another way to look at it is this: these days so many children are allergic to nuts. Parents won't even buy food from companies that manufacture products containing nuts, even if they know that one particular product contains no nuts. This companies are now forced to print: "may contain traces of nuts". The same would have to be done with beer, making many of their customer base apprehensive to use. When it comes to beer, if it's not broken, don't fix it. It is fine the way it is, so don't temper with it!


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 26, 2023
Valid points!, especially how budweiser play SAD spin and missed [1 (https://www.businessnewsdaily.com/2649-sex-sells-more.html)] what probably would had have pass if used CBD as libido bait [2 (https://www.healthline.com/health/healthy-sex/cbd-and-libido)][2 (https://www.healthline.com/health/cbd-sex-effectiveness#best-options-for-sex)] altho that would be kinky bargain for male consumers [3 (https://archive.is/zNgaK#selection-1905.3-1911.60)] unless there is some intentional peer'review conspiracy [4 (https://archive.is/PSuNw#selection-1917.1-1917.80)][5 (https://archive.is/IphWY#selection-9477.0-9735.20)] so would be discouraged mass CBD hype in food&beverage industry!?, altho on one hand if depop agenda was indeed part of modern eugenics inc. such claim would had have been ace for "them", yet boosting the population enmasse by CBD its heresy for "them" from aspect of longevity of the useless eaters [6 (https://archive.is/f4mLd#selection-2417.149-2419.1)] and all that smoothly flushed by "mixed results" in studies!, again wonder whether in this case also synthetic cbd wasnt used!?, and how obvious are discrepancies between studies with natural extract and synthetic derivations noted in the first page of this thread, practically like this can be played constantly any eventual positive acclamation for benefits of CBD!, and think the same spin even from opposite perspective can be exploited easily [6 (https://biology-forums.com/index.php?topic=2054825.msg5419163#msg5419163)]   



Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on May 27, 2023
What is good to Yell about is the rush after cannabis gmo, so be clever before all natural seeds are decimated by cross pollination with gmo strains which even till now are present but now its becoming trend that threatens the indigenous strains [1 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8197860/)][1 (https://www.alchimiaweb.com/blogen/crispr-cannabis/)] altho there are other ways of forced evolution that altho "organic" still have own "manufacturing" risks [2 (https://youtu.be/tpehlYztWzs)] So this is maybe last hour for making autochthonous seed banks eg. in Macedonia we have some very unique wild CBD strains but who is even aware here about this need!?

Also I would like to wonder bit more about infertility risks, so in the next footnote it could be seen info about comparison study that screened smokers and nonsmokers coming to conclusion that the quality of semen was lower in smokers but as in the comments of the first video say what could be due to smoking [3 (https://youtu.be/QrMzD1vqRok)][3 (https://youtu.be/HkvJ9u6c4Vk)] on top even how these videos are presented looks like agitprop instead scientific language, making fuzz actually instead to be addressed the probable reasons and what kind of studies will bring clarity!, as if fearporn narrative should be sold, again dont need to wonder why!, practically invitro mouse knockouts should be done in parallel with natural extract and synthetic chemical so would be seen comparison in same research, also where smokers are target group there it can be seen per'se CBD as culprit for negative results coz there are many variables that can mislead!, however we should maybe open new ontopic thread where this issue will be further explored!, bottom line I'll understand trough THC to be affected semen but CBD cmon!, how?

https://blog.scrcivf.com/cbd-and-fertility (https://archive.is/fH7HP#selection-1285.0-1285.137)








Title: Re: CBD as T-Cell booster studies
Post by: duddy on Jun 2, 2023
"Endocannabinoid receptors have been found in sperm and the female reproductive tract. Because of this, it’s thought that they can improve a sperm’s ability to fertilize an egg, boost ovarian function and follicle maturation. In short, that CBD can be a natural way to boost fertility with minimal negative side effects. There is yet to be strong evidence to support this theory."

Source: https://archive.is/fH7HP#selection-1285.0-1289.203

That's really pushing it for me. >99% of humans don't have a fertility problem to begin with. Why would anyone using CBD oils, which naturally would be impossible to extract for this purpose? This sounds like crazy talk to me; seems like the industry is trying to bite more off than they can (or should) chew.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Jun 2, 2023
It sounds opportunistic if seen through remedy hype glasses, but if its seen ECS System eg. like crucial layer to the Lymph System then its not hard to grasp its vast impact on the Organism, actually my motive label the Natural CBD as Elixir ...

... yet till big'pharma dont hijack most of the market by gmo seeds and flush patented remedies till then it will do its best to suppress the importance of CBD i.e. if lose profit if shouted then "they" would need to compensate [1 (https://youtu.be/sY8MIoki9BQ?t=4834)][1 (https://archive.is/wGIdt#selection-12753.3-12855.23)]  the question is why academia still keep quiet or is silenced easily!?, tho again here we are going in circles coz the hijacked peer'review'process!, altho guess if pop up dedicated thematic academic eforums things at least could move in the right direction!, in essence we have still not fully understood the CBD System as dr. Prakash Nagarkatti said in 2011 [2 (https://youtu.be/JZWgpmREyzs?t=2627)][2 (https://archive.is/4VWLM#selection-7391.25-7433.10)] but even if we do that notion will not be popularized as I've said till big'pharma dont have grip on the splif!, yet again also imagine the fears of malthusians if the useless eaters have longevity at hand for free!

https://medium.com/@madeforcbd/the-human-endocannabinoid-system-861cae70f300 (https://archive.is/ocAMr#selection-453.0-453.11)

 


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Jun 5, 2023
actually my motive to label the Natural CBD as an Elixir ...

important to correct the typo so would accent how important is this topic regards immunology!, but who is Brave enough among the academicians to push up further this notion till reach mainstream acceptance and CBD is offered as prescribed immunization alternative!, yet we still need to determine not just why synthetic-cbd is evil while Natural CBD Blessing for our immunity, altho there is also some new notion that different natural cbd strains of Marijuana have  variation in its antiinflamantory effects, in the next study by observation of the Lymphocyte Homing [1 (https://en.wikipedia.org/wiki/Lymphocyte_homing_receptor)] Yo Homeboys Seek Carefully what kind of Weed is candidate for Elixir Label ... do someone has CBD-X seeds :)

https://www.frontiersin.org/articles/10.3389/fimmu.2022.875546/full (https://www.frontiersin.org/articles/10.3389/fimmu.2022.875546/full)





Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Jun 6, 2023
This last study above is enough good pivot to stir many in harvesting mode of wild hemp, altho it would need to find labs that will check the content proportion what is not so wide spread occurrence even in usA but where most of the focus is on high potent thc strains [1 (https://youtu.be/KnBkWQr1rtc)] thus its question whether offer such option for random check of whatever someone will send them!?, I am really not sure when but it could become regular trend in every lab eventually if this notion about immunological potential of CBD become normal hype ... its interesting eg. that on the european market there are various mostly low level CBD extracts [2 (https://archive.is/mPv9D#selection-859.0-915.1)] altho guess its not hard to be derived exact proportions, still all this asks for further taming of the right balance of phytocannabinoids but also the right dosage for different organism hm for what there is large pool of volunteers at disposal for sure but foremost it should be standardized methodology for analyzing and reporting of health effects in eventual groups of homecooks that would refer spicing their food with raw CBD elixir, guess also by the bioresonance logic in various circumstances different balance of cbd thc will open the lymph valve for T-Cells ... anyway till then many will need to put faith in their own luck for chase of the right balance, but it should be enough comfy notion that ECS System is main part of our bodies thus whatever intake of CBD eventually will have beneficial effects for healthy person as prevention condiment to the food, while sick people could and need to experiment with greater focus, I'll add quantity dont needs always to be solution but as is shown by the CBD-X point in the last study fine tuned extract will gain extra results even without extra pains [3 (https://www.youtube.com/results?search_query=anatoly+gym+cleaner)]


Title: Re: CBD as T-Cell booster studies
Post by: bio_man on Jun 18, 2023
Finding labs that offer random checks for content proportions might be a challenge, especially considering the current emphasis on THC strains. But as the idea of cbd's immunological potential gains traction, it is possible that the demand for such testing will increase, leading to a broader availability of lab services. In the European market, there are already various CBD extracts available, although determining the exact proportions may not always be difficult. Nevertheless, standardization of methodology for analyzing and reporting health effects, particularly in groups of individuals experimenting with CBD in homemade food preparations, would be beneficial. This could help establish a clearer understanding of the effects of different balances of CBD and THC in various circumstances.


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Jun 23, 2023
Logically ... but first we would need to put some greater effort in reevaluating all processes regards CBD eg. in context of bioresonance [1 (https://biology-forums.com/index.php?topic=2054205.msg5424015#msg5424015)] so would be grasp the mechanisms like when CBD acts as antiinflammatory substance [2 (https://archive.is/qH81n#selection-1639.0-1649.231)] and when as lymphocyte booster [3 (https://archive.is/0A4YG#selection-6971.0-6989.1)] also how which balance between CBD and THC activates particular mechanism [4 (https://biology-forums.com/index.php?topic=1975202.msg5421423#msg5421423)] also how on the same acts electromagnetic pollution or chemical and/or metal toxicity in the organism, practically now we need broadened research way beyond the current mostly private funding hype, but will that become reality it will be known maybe after the next global economic depression when logically big pharma grip on the system should loosen if and only if eugenics&transhumanism also faint away from the picture!


Title: Re: CBD as T-Cell booster studies
Post by: Odiseizam on Jul 28, 2023
we need to put some greater effort in reevaluating all processes regards CBD eg. in context of bioresonance [1 (https://biology-forums.com/index.php?topic=2054205.msg5424015#msg5424015)] so would grasp the mechanisms like ...

The current understanding of nature on pure chemical reductionist level will push us further in middle of nowhere regards the conflicting studies, and at best the true understanding about CBD will be postponed, coz whatever useful study of cbd extracts will be devaluated by repeated one with synthetic cbd, also not rarely the preclinical knockouts will differ with the clinical studies [1 (https://archive.is/Q4gRY#selection-3427.0-3442.0)] what could be due to bioresonance but also still not fully mastered interaction of all phytocannabidoids among themselves [2 (https://archive.is/2h0jA#selection-913.2-913.155)][3 (https://biology-forums.com/index.php?topic=1975202.msg5421423#msg5421423)] and foremost seeing how expensive is such extract now [2 (https://archive.is/2h0jA#selection-1077.113-1077.199)] it looks like it will be intentionally stalled as widespread prescribed medicine  ... thus my advice would be if someone really wants to reach effective natural immunization of its population rush for eg. rural legalization  and/or extra balancing by heavily subsidized sport culture [4 (https://biology-forums.com/index.php?topic=1975202.msg5419068#msg5419068)][4 (https://archive.is/Xy5wr#selection-8745.138-8745.276)] and let citizens to experiment the right dosage on themselves for themselves cheaply!

For what tho first of all it would be needed local wide eTOS hype
[5 (https://biology-forums.com/index.php?topic=2060558.msg5429804#msg5429804)] where the majority of experts will measure out the right model of legalization and right after through referendum to be cemented the will of citizens for the right to own healing herb cultivation!, probably such momentum should stir some small political party and by opening dedicated legalization eforum to built up momentum for referendum!, otherwise waiting on plutocrats to deliver effective and lasting legalization will be ridiculous if not futile, simply "they" will lust even then in corrupt mode trying to milk some from licensing or molesting the licensed around taxation etc. etc. probable skims that again will affect the chance for wide natural immunization!