Biology Forums - Study Force

The pedigrees below are for a dominant disease where individuals with the dominant disease allele (D) are affected. Individuals that were alive were also screened for a polymorphic DNA marker that has six alleles identified as P1, P2, P3, P4, P5, and P6.

a)	In Family B, explain why the P1 marker cannot be assumed to be transmitted with the dominant

allele given that there is no haplotype data for the first generation.

b)	In Family A, how does the information regarding the haplotype of individuals in the first

generation allow you to determine the allelic phase of the disease?
"Use Figure 5.15 in Chapter 5, page 169 from main title."

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