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Biology-Related Homework Help Genetics and Developmental Biology Topic started by: MZ Mai on Jan 4, 2022



Title: What is the purpose of the 3'-to-5' exonuclease activity of DNA Polymerase?
Post by: MZ Mai on Jan 4, 2022
What is the purpose of the 3'-to-5' exonuclease activity of DNA Polymerase?

▸ Some polymerases do not have exonuclease activity.

▸ Remove mismatched nucleotides in the newly synthesized strand.

▸ Degrade excessive nucleotides on Okazaki fragments.

▸ Remove mismatched nucleotides in the template strand.

▸ Removing mismatched nucleotides at the polymerase active site increases the rate of synthesis in the 5' to 3' direction.


Title: What is the purpose of the 3'-to-5' exonuclease activity of DNA Polymerase?
Post by: rileyjones420 on Jan 4, 2022
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