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Title: Why are leading and lagging strand primers removed rather than joined with Okazaki fragments? Post by: cmperez1988 on Jan 4, 2022 Why are leading and lagging strand primers removed rather than joined with Okazaki fragments?
▸ The primers do not hydrogen bond to the template strand correctly. ▸ They have to be removed for leading and lagging strand synthesis to begin. ▸ Primers are too short to efficiently bind to Okazaki fragments. ▸ They contain nucleotides with 2'OH groups, and are targeted for excision by DNA Polymerase. ▸ They lack the 3' OH that would permit them to be covalently linked to the Okazaki fragments. Title: Why are leading and lagging strand primers removed rather than joined with Okazaki fragments? Post by: KellyNguy on Jan 4, 2022 Content hidden
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