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Title: Why do origins of replication in various bacteria have conserved DNA consensus sequences? Post by: Golson on Jan 4, 2022 Why do origins of replication in various bacteria have conserved DNA consensus sequences?
▸ Consensus sequences are found throughout bacterial genomes and so would be found at the origin as well. ▸ The consensus sequence allows the origin to wrap into a circle and recruit replication initiation proteins. ▸ It is more efficient to use the same sequence multiple times in different genomes than to change it. ▸ Fewer mutations in the DNA occur at the very beginning of replication at the origin, hence why they are conserved as consensus sequences. ▸ Origins need to be recognized by replication initiation proteins to open up their AT-rich regions. Title: Why do origins of replication in various bacteria have conserved DNA consensus sequences? Post by: PHchick on Jan 4, 2022 Content hidden
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