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Title: Why are eukaryotic mRNAs not polycistronic, unlike some bacterial transcripts? Post by: kyliesalm on Jan 4, 2022 Why are eukaryotic mRNAs not polycistronic, unlike some bacterial transcripts?
▸ Eukaryote's genetic code is non-overlapping, and so coding sequences cannot overlap on the same mRNA. ▸ Eukaryotes have more complex translational machinery than bacteria that is also less efficient in initiating translation. ▸ Eukaryotic mRNAs are generally shorter than bacteria mRNAs, and so do not contain sufficient information to encode additional polypeptides. ▸ Bacteria couple their translation with transcription, while eukaryotes do not. ▸ The eukaryotic ribosome must bind to the 5' end of the mRNA and scan, while the bacterial ribosome can bind to a Shine-Delgarno sequence anywhere in the mRNA. Title: Why are eukaryotic mRNAs not polycistronic, unlike some bacterial transcripts? Post by: kater28 on Jan 4, 2022 Content hidden
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