Title: Which lists the potential steps for genetic therapy for mice with sickle cell disease (S/S) in the ...
Post by: robbie on Jan 4, 2022
Which lists the potential steps for genetic therapy for mice with sickle cell disease (β S/β S) in the correct order? | I. | Differentiation of iPS cells into hematopoietic progenitor (HP) cells by infecting with retrovirus |
expressing HoxB4. | II. | Reprogramming tail fibroblasts into induced pluripotent stem (iPS) cells by infecting them with |
viral vectors containing transcription factors. | III. | Infection with a viral vector expressing Cre recombinase to remove transcription factor(s) from |
from iPS cells. | IV. | Transplantation of corrected (βA/βA) hematopoietic cells back into irradiated mice. |
| V. | Homologous recombination with βS and wild-type βA allele via CRISPR-Cas9 genome editing. |
▸ I, II, III, V, IV ▸ II, III, V, I, IV ▸ V, III, IV, I, II ▸ V, III, I, IV, II ▸ II, III, IV, V, I
Title: Which lists the potential steps for genetic therapy for mice with sickle cell disease (S/S) in the ...
Post by: Andylai01 on Jan 4, 2022
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