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Title: A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced ... Post by: Jappyde1 on Jan 4, 2022 A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced from a sample of Antarctic ice. The cell/organism that the chromosome came from is not known, however it yielded a single circular chromosome. You are asked to run a BLAST search to help this researcher identify the most related organism in GenBank. What would be the best strategy?
▸ Compare the most unusual portion of this newly-discovered chromosome to al known animal genomes. ▸ Perform many careful one-by-one comparisons between the newly-discovered DNA sequence and species selected from GenBank, one at a time. ▸ Use several ~1000bp portions of the DNA sequence to search for the closest matches from among the entire available database. ▸ Look for a nearly identical match to a very small part (20-40 bp) of the chromosome from all known ice bacteria. ▸ Look for an exact match to the whole chromosome. Title: A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced ... Post by: amiritate03 on Jan 4, 2022 Content hidden
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