Title: Vascular VS Nervous. Post by: CarbonRobot on Apr 23, 2022 If the body created more blood vessels would it also create more nerves? How intertwined are these two systems? Which proceeds which? Do they often interfere with one another or are they nearly step for step?
Title: Re: Vascular VS Nervous. Post by: duddy on Apr 24, 2022 They're very much intertwined.
According to this article (https://www.nature.com/articles/nrg1158), neurons and blood vessels share common genetic pathways to acquire their fate, grow, pattern and navigate, and how both the vascular and neural systems are linked. Some other take away points are listed below:
Wish I had access to the article. If anyone here has access to Nature articles, please share it :) Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 24, 2022 I have read that NAD+ has shown to improve vascular health and even cause new blood vessels to grow which makes me wonder if new neurons might also grow along with them.
I might have pressure on my trigeminal nerve from possibly a blood vessel. I am hoping increasing NAD+ might help nerves and blood vessels assist one another versus get in each other's way. Brain surgery is always a bad risk. Title: Re: Vascular VS Nervous. Post by: bio_man on Apr 24, 2022 Here you go, boys
Title: Re: Vascular VS Nervous. Post by: duddy on Apr 24, 2022 Much appreciated!!
Quote I have read that NAD+ has shown to improve vascular health and even cause new blood vessels to grow which makes me wonder if new neurons might also grow along with them. If that is true (and I'm not verifying), with vascular regeneration comes neurogenesis. I might have pressure on my trigeminal nerve from possibly a blood vessel. Sounds serious man, has this been diagnosed by a medical professional? Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 24, 2022 No diagnosis yet. Just a vague inference in my MRI report. Neurologist didn't seem concerned but suggested I talk with a surgical specialist if I want to for more information. Probably not indicated for surgery though. I hear this type of thing can be really incapacitating at its worst. I'm not too worried, but I love to nip things in the bud when a problem is relatively slight.
Title: Re: Vascular VS Nervous. Post by: duddy on Apr 25, 2022 There's no harm in using supplements to your health. People think that everything must be "FDA-approved" to work, but that's far from true. I learned of one guy who had chronic hepatitis B that took milk thistle (Silybum marianum) from the moment he learned of his condition - milk thistle is an ancient herb known to increase liver function. Literally the virus never progressed to liver disease or cancer; he lives by it to this day. So if there's a supplement that claims to aid in NAD+ generation, continue taking it
Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 25, 2022 Well so far NAD+ precursors have only shown in humans to increase NAD+ in the liver so they are still testing those supplements. As for milk thistle I'm allergic. I think Hep B usually self resolves, and if it doesn't they have antivirals.
Title: Re: Vascular VS Nervous. Post by: bio_man on Apr 26, 2022 How is NAD+ taken, anyway? If orally, isn't it catabolized by the digestive system before it reaches its target?
I think Hep B usually self resolves, and if it doesn't they have antivirals. Hepatitis is a leading cause of death worldwide. The last I checked, it takes more lives than HIV. Chronic hepatitis means that it is there to stay, compared to acute. Antivirals decrease the viral load, but doesn't eliminate the virus. Title: Re: Vascular VS Nervous. Post by: duddy on Apr 26, 2022 How is NAD+ taken, anyway? If orally, isn't it catabolized by the digestive system before it reaches its target? They are NAD precursors. For example, as pointed out here (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352172/), nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD+) precursors, due to its numerous potential health benefits mediated via elevated NAD+ content in the body. It's well documented, actually: Oral supplementation with NR has been shown to increase NAD+ levels in multiple tissues, along with increased SIRT activity [10,11], improved mitochondrial function [37], and regenerative potential of stem cells [38] Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 26, 2022 Well HIV meds can keep its virus load to undetectable so nobody needs to die of HIV anymore. As for Hepatitis there are more types than letters of the alphabet. The first 5 I think are the most treated ones. Hep C is curable in most cases now. According to Google search B is very treatable too.
Dr. David Sinclair says NMN is a superior precursor for creating NAD+ in the cells. In mice models anyway most of their cells create NAD+ readily. Humans have been for fickle. They are creating new boosters that contain NMN and something else to better the absorption. That is still in human trials. Title: Re: Vascular VS Nervous. Post by: bio_man on Apr 27, 2022 I might have pressure on my trigeminal nerve from possibly a blood vessel. I am hoping increasing NAD+ might help nerves and blood vessels assist one another versus get in each other's way. Brain surgery is always a bad risk. So the MRI was able to identify this particular area, and you're making the assumption it is the trigeminal nerve. Do you experience trouble talking or chewing, what about facial numbness or pain? These are symptoms of trigeminal nerve injury. Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 27, 2022 I might have pressure on my trigeminal nerve from possibly a blood vessel. I am hoping increasing NAD+ might help nerves and blood vessels assist one another versus get in each other's way. Brain surgery is always a bad risk. So the MRI was able to identify this particular area, and you're making the assumption it is the trigeminal nerve. Do you experience trouble talking or chewing, what about facial numbness or pain? These are symptoms of trigeminal nerve injury. I don't have most of the physical symptoms but dull feeling around one eye and sharp pains around temple or near ear. The report said there might be some contact, but nothing so major that the myelin shealth is rubbed off. Nurse practitioner wasn't concerned but ordered MRA to accompany the MRI for good measures. How do I increase post credits again? Replying to other posts hasn't done anything lately. Title: Re: Vascular VS Nervous. Post by: bio_man on Apr 27, 2022 How do I increase post credits again? Replying to other posts hasn't done anything lately. Currently, it is configured like this. I altered it this morning. (https://biology-forums.com/gallery/45/6_27_04_22_9_45_23.png) (https://biology-forums.com/index.php?action=gallery;sa=view&id=45017) Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 27, 2022 How do I increase post credits again? Replying to other posts hasn't done anything lately. Currently, it is configured like this. I altered it this morning. (https://biology-forums.com/gallery/45/6_27_04_22_9_45_23.png) (https://biology-forums.com/index.php?action=gallery;sa=view&id=45017) Don't understand the subtleties but replying to posts doesn't seem to work. Title: Re: Vascular VS Nervous. Post by: bio_man on Apr 27, 2022 You actually helped me discover a critical error in the code that has now been corrected. To show our appreciate, you should receive a free credit pack for all your troubles
Title: Re: Vascular VS Nervous. Post by: CarbonRobot on Apr 28, 2022 You actually helped me discover a critical error in the code that has now been corrected. To show our appreciate, you should receive a free credit pack for all your troubles Thanks. |