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Title: Interferon tau Post by: gautam on Sep 23, 2010 Is it feasible/possible to measure the interferon tau (NOT the ISG) in blood sample of inseminated cows ?
I was searching the for " determination of interferon tau". But all searched results show "interferon tau stimulated genes". I am interested only on "interferon tau", NOT on "interferon stimulated genes". I would be grateful if someone suggests me how to determine "interferon tau" in inseminated cows (not the ISG). Title: Re: Interferon tau Post by: Biology Forums on Sep 23, 2010 Hey Gautam, welcome!
Please post your question in a single category. It will be answered shortly. Title: Re: Interferon tau Post by: bio_man on Sep 23, 2010 Interferon tau is the signal from the developing embryo to the mother that she is pregnant. It is secreted by the trophoblast cells into the uterine lumen in days 13-21 of pregnancy. It decreases endometrial oxytocin receptors, which then cannot stimulate PGF-2-alpha synthesis, preventing luteolysis. It promotes uterine implantation by increasing protein synthesis in glands.
I found the following papers to aid you: 1) http://www.ncbi.nlm.nih.gov/pubmed/20554404 (http://www.ncbi.nlm.nih.gov/pubmed/20554404) Measurement of interferon-tau (IFN-tau) stimulated gene expression in blood leukocytes for pregnancy diagnosis within 18-20d after insemination in dairy cattle. 2) http://www.ncbi.nlm.nih.gov/pubmed/11343838 (http://www.ncbi.nlm.nih.gov/pubmed/11343838) Genetic and environmental determinants of interferon-tau secretion by in vivo- and in vitro-derived bovine blastocysts. 3) View Attachment 1 4) View Attachment 2: Complex Induction of Bovine Uterine Proteins by Interferon-Tau1 5) http://www.biomedsearch.com/nih/Measurement-interferon-tau-IFN-stimulated/20554404.html (http://www.biomedsearch.com/nih/Measurement-interferon-tau-IFN-stimulated/20554404.html) 6) http://onlinelibrary.wiley.com/doi/10.1002/mrd.20431/abstract (http://onlinelibrary.wiley.com/doi/10.1002/mrd.20431/abstract) In vivo expression of interferon tau mRNA by the embryonic trophoblast and uterine concentrations of interferon tau protein during early pregnancy in the cow 7) http://www.reproduction-online.org/cgi/content/abstract/121/1/175 (http://www.reproduction-online.org/cgi/content/abstract/121/1/175) (Free) Relationship between maternal endocrine environment, early embryo development and inhibition of the luteolytic mechanism in cows 8 ) http://pubget.com/search?q=authors:%22J%20C%20Green%22 (http://pubget.com/search?q=authors:%22J%20C%20Green%22) As a member of Biology-forums.com, we can purchase this paper for you free of charge. |