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Title: what are the functions of reticular networks in the lymph nodes? Post by: Gyousuf on Mar 31, 2015 :)
Title: Re: what are the functions of reticular networks in the lymph nodes? Post by: Puja Ghosh on Mar 31, 2015 Lymph nodes are encapsulated bean shaped structures containing a reticular network packed with lymphocytes, macrophages and dendritic cells. The sophisticated microarchitecture of the lymph node, which is largely supported by a reticular network of fibroblastic reticular cells (FRCs) and extracellular matrix, is essential for immune function.FRCs form the elaborate network and remodel it in response to lymphocyte activation.Multiple chemokines produced by FRCs induced T cell and dendritic cell chemotaxis and adhesion to the FRC surface. Signals from lymphocytes induce FRCs to form the network that supports the movement and interactions of immune effectors within the lymph node. (Tomoya Katakai,2004)
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