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Biology-Related Homework Help Genetics and Developmental Biology Topic started by: louiseinger on May 25, 2015



Title: What other type of protein/s is FtsZ-mt similar to?
Post by: louiseinger on May 25, 2015
This question is part of a bioinformatics assignment for Uni.

Essentially, I am looking at the protein FtsZ-mt.  We are asked to describe similar proteins, as well as what other types of CELLS use versions of this protein to divide themselves.

So far, I have established that the protein FtsZ is used in bacterial and prokaryotic cells.  I am unsure if it is used amongst anything else? 
I also have no idea of similar proteins because search results tend to yield 'possible' proteins that are 'thought to' be involved in cellular/organelle division, and these results extend farther than the horizon so it's difficult to narrow down.

Hope to hear from someone!


Title: Re: What other type of protein/s is FtsZ-mt similar to?
Post by: bio_man on May 25, 2015
Hi Louiseinger,

Probably a stupid question, but have you tried using BLAST?

http://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE=Proteins



Title: Re: What other type of protein/s is FtsZ-mt similar to?
Post by: louiseinger on May 25, 2015
I used BLAST to find the name of the genus that the protein sequence came from but am unsure how to use it to find similar proteins?


Title: Re: What other type of protein/s is FtsZ-mt similar to?
Post by: bio_man on May 25, 2015
That can be done, if I recall. I just don't recall step-by-step, which is probably what you need. I'll leave you with these two links, maybe you can find some useful information from them.

http://www.ncbi.nlm.nih.gov/guide/howto/find-homolog-gene/
http://blast.ncbi.nlm.nih.gov/Blast.cgi


Title: Re: What other type of protein/s is FtsZ-mt similar to?
Post by: n.us.c on May 27, 2015
Doing this assignment right now too, but like bio_man said, two other names come up when the BLAST thing is entered.
Maybe the two alignments are the similar proteins (Parvimonas micra strain KCOM 1535,  and Clostridium sp. M2/40 replicon M2/40_rep1) ?