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Title: X-linked inheritance and X-inactivation Post by: daniellionyang on Dec 29, 2015 My biology textbook states that X inactivation happens randomly. However, X-linked dominant and X-linked recessive traits only follow either dominant or recessive patterns. What's with this disconnect? Thanks!
Title: Re: X-linked inheritance and X-inactivation Post by: bio_man on Dec 30, 2015 Good question. According to a Wikipedia article:
Some scholars have suggested discontinuing the terms dominant and recessive when referring to X-linked inheritance due to the multiple mechanisms that can result in the expression of X-linked traits in females, which include cell autonomous expression, skewed X-inactivation, clonal expansion, and somatic mosaicism. |