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Title: Is there tRNA that has an anticodon that will fit the stop codon? Post by: mido1770 on Sep 14, 2012 I'm trying to figure out is there a tRNA anticodon that will fit the stop codon? If not is that the reason it stops?
Title: Is there tRNA that has an anticodon that will fit the stop codon? Post by: midnightxxmal on Sep 14, 2012 Instead of a tRNA carrying an amino acid, a "release factor" binds to one of the stop codons (UAG, UAA, or UGA). I believe that the release factor still contains an anticodon on it, hence why it can hydrogen-bond to the codon in the first place.
Anyway, release factors work simply because there is no amino acid on it; there is nothing for the polypeptide to form a peptide bond with. Thus, the polypeptide is released. |