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Title: please help! physio 9.0 exercise 3 activity 8 Post by: margaretr1989 on Feb 10, 2013 1. You have just observed that each action potential in a burst can trigger additional neurotransmitter release. If calcium ions are removed from the extracellular solution, what will happen to neurotransmitter release at the nerve terminal?
2. What will happen to the amount of neurotransmitter release when low amounts of calcium are added back to the extracellular solution? 3. what will happen to neurotransmitter release when magnesium is added to extracellular solution? 4. If you added more sodium to extracellular solution, could the sodium substitute for the missing calcium? 5. how does botulinum toxin block synaptic transmission? why is it used for cosmetic procedures? thank you!! your answers help me figure out how you came to that conclusion and I am able to understand it better. I am having a hard time with these... the book doesn't give you much help/insight so anything is greatly appreciated!! Title: Re: please help! physio 9.0 exercise 3 activity 8 Post by: bio_man on Feb 11, 2013 Hi there, please follow forum rules of two questions per thread:
1. It is unlikely that sodium could substitute for calcium since the addition of magnesium blocked the calcium channels. 2. Botulinum toxin blocks the release of acetylcholine from the axon terminal. It is used in cosmetic procedures because it results in paralysis of the muscles that are contracting and causing the wrinkles. |