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You decide to cross the reciprocal translocation strain to a pure (black, sepia)
You decide to cross the reciprocal translocation strain to a pure (black, sepia) line to generate female F1 flies that are both translocation heterozygotes and BbSs dihybrids.
You then backcross these F1 females to males from the pure (black, sepia) line. This diagram shows synapsis in the F1 females. (In the diagram, NII = normal chromosome II; TII = translocated chromos
Which of the following statements about the prevalence of neurological disease in the U.S. today is
Which of the following statements about the prevalence of neurological disease in the U.S. today is false?
a. There are more people diagnosed with stroke than with epilepsy. b. There are more people diagnosed with Alzheimer's disease than with head trauma. c. There are more people diagnosed with cerebral palsy than with epilepsy. d. There are more peop
Where does the cut take place in palindrome sequence
In the case of restriction enzymes, I know that it chooses Palindromes, but where does the exact cut take place? Is it always between A and T base pairs or Can it occur between any base pairs in a palindrome sequence.
When are the major regulatory points in the cell cycle?
early G1 phase (M/G1 checkpoint) late G1 phase (G1/S checkpoint) S phase (S checkpoint) early G2 phase (S/G2 checkpoint) late G2 phase (G2/M checkpoint) M phase (M checkpoint)
What would be the size in base pairs of the largest and smallest amplicons that would be expected if
Relevant details of the STRs are as follows
TH01
Chromosomal location: 11p15.5 (tyrosine hydroxylase, 1st intron) Repeat motif: TCAT (GenBank top strand) although AATG (bottom strand) often used. Note that variants with a [AATG]nATG[AATG]n structure quite common e.g. [AATG]6ATG[AATG]3 would be 9.3 repeats. Allele range: 3-14
What is the map distance to 4 significant figures between the A and B loci?
"These are the results of a three point test cross in Drosophila for the three loci ABC: aCB = 1444, ACb = 245, AcB = 1222, ACB = 2212, aCb = 1333, acB = 299, Acb = 1499, acb = 2333. What is the map distance to 4 significant figures between the A and B loci? Hint: Establish gene order first."
What is the map distance to 4 significant figures between A and B loci?
"These are the results of a three point test cross in Drosophila for the three loci ABC: aCB = 354, ACb = 28, AcB = 261, ACB = 666, aCb = 256, acB = 35, Acb = 309, acb = 578. What is the map distance to 4 significant figures between the A and B loci? Hint: Establish gene order first."
What happens if region 1-100 is removed from the Gal4p sequence?
Can someone verify the validity of my statements? (This topic is extremely confusing to me)
A) What happens if region 1-100 is removed from the Gal4p sequence? Gal4p is a protein encoded by the GAL4 gene and the entire protein consists of a total of 881 amino acids. Section 1-98 of the entire Gal4 protein is called the “DNA binding domain.” In order for transc
Was Lewis just mapping them on a linkage map based on mutations?
Hi guys,
So I've spent a few days reviewing the genetic tools used in labs, but can't quite find the distinction between a few of the methods.
1. RT-PCR is used to determine if a specific gene is expressed; however, RNA-seq appears to do the same thing. I understand that RT-PCR uses a specific primer and thus tests the expression of one gene. Does RNA
Visualizing exons and their respective trancripts and protein domains.
I am building a script that takes exons from a particular gene and then plots them by their base pair coordinates on a 2D graph. Using data from Ensembl, I can match each exon to its respective transcript and protein domain.
I use data from Ensemble to match each domain to the gene base pairs responsible for its formation; I can then plot the protein domains above their r
Use the following table of progeny phenotypes for 7 different deletions
Deletions can be used to map genes along a chromosome. In order to do this a series of crosses in which one parent is homozygous for a mutant allele is crossed with the other parent that is homozygous for a partial deletion of the region. The progeny are scored to determine whether they have the mutant phenotype ("m") or the wild-type phenotype ("+"). If a mutati
Two different genes control the expression of coat colour in an organism.
3. Two different genes control the expression of coat colour in an organism. The allele B produces a black coat colour and the allele G produces a gray-striped coat. The gene B influences the expression of gene G. The gray-stripped coat pattern appears only when gene B is homozygous recessive. An albino (coat colour lacking) occurs when both genes are homozygous. A pure-breedin
Two cats having short tails are mated and have 11 kittens. The offspring (kitte
Two cats having short tails are mated and have 11 kittens. The offspring (kittens) from this cross yield interesting results. Of the 11 kittens, 3 are born with long tails, 2 are born with no tails and 6 are born with short tails. What is the simplest genetic explanation for this litter of kittens and their parents? Provide the genotypes of the parents and al
tRNAs involved in the process occupy a series of sites on the complexed chromoso
Once elongation is underway, tRNAs involved in the process occupy a series of sites on the complexed ribosome. The occupation of sites occurs in the following order.
translate this into protein using the genetic code table.
Below is a sequence of double stranded DNA from a bacterium. Based on what you know about bacterial transcription and translation, put an “X” next to the strand that is most likely to be the template strand for transcription and give a brief answer for your choice (5-10 words). Then, • clearly underline the likely coding sequence • transcribe it into mRNA
Though we often think of genes in terms of the phenotypes they produce.......
Though weoften think of genes in terms of the phenotypes they produce (e.g., curly leaves, flaky tail, brown eyes), the molecular function of most genes is to encode proteins. Many cellular proteins function as enzymes. The table that follows describes the map distance between six different genes that encode six different enzymes: Ada, adenosine deaminase, Hao-1, hydroxy
The table shown lists the approximate new mutation rates for three autosomal dom
The table shown lists the approximate new mutation rates for three autosomal dominant human diseases. Trait Mutations per 106 gametes Retinoblastoma (tumor of the retina) 20 Achondroplasia (statural dwarfism) 80 Neurofibromatosis (tumor of nervous tissue) 220
In a series of 50000 consecutive live births recorded in a
The likelihood of having identical children (who are not twins)
So I figure if you have enough babies (probably in the billions) you'd eventually get one that was essentially genetically and/or aesthetically identical to another. Could anyone give me any background information and numbers regarding the likelihood of this?
The GTP binding domain of elongation factor Tu (EF-Tu) and elongation factor 1α
The GTP binding domain of elongation factor Tu (EF-Tu) and elongation factor 1α (EF-1 α) contains an eight amino acids conserved region, with the sequence FIKNMITG (using the one letter code). Here you are designing only one of the two primers required for PCR.
a. If you were using this region to design a primer to amplify by PCR the sense strand of EF-Tu/EF-1
The first two prenancies for a couple result in late term stillbirths...
The first two pregnancies for a couple result in late term stillbirths. The reproductive histories of both families, over 3 generations, were compiled. A pattern of frequent miscarriages, stillbirths and malformed babies that died shortly after birth were seen in the husband's family. The husband has a karyotype done, which shows that he has the normal number of chromosomes. Wh
The binding of cAMP to the CAP protein involves numerous electrostatic interacti
The binding of cAMP to the CAP protein involves numerous electrostatic interactions. Most of the interactions are hydrogen bonds between cAMP atoms and the side chains of various amino acids in the CAP protein. Which of the following is a salt bridge rather than a hydrogen bond?
Hi I'm currently taking genetics at my school and the section on haploid genetics (i.e. Neurospora) has me dazed. Can anyone explain clearly how tetrad analyis works, what PD,NPD,T all represent and how they all come together in the so-called Perkin's formula? (the derivation) Thanks!
Stand as far away from the corner of a room as you can, moving to a larger room might help.
directions: stand as far away from the corner of a room as you can, moving to a larger room might help. with both eyes open hold a pencil at arms length in front of you, placing the pencil in the corner. now, close your left eye and observe what happens to the image of the pencil. alternate by closing only your right eye and observe what happens.
Sex linked traits, Two Genes, Two Traits, Complete Dominance
A corn plant that originated from a purple, starchy seed is cross pollinated with a plant that originiated form a yellow, sweet seed. The seeds on a cob from the resulting cross exhibit the following numbers: Purple, starchy --104; Purple, sweet --96; Yellow, starchy --101; and Yellow, sweet --110. Purple and starchy are both dominant alleles. What genotype of the purple starchy see
In cats, an x-linked pair of alleles, B and B', determines the color of fur. The allele "B" for yellow is codominant with B' for black so that BB' cats are tortoise shelled, a splotchy mixture of yellow and black hairs. You and a friend are strolling down the street and see a tortoise shell cat. You bet your
here is the data, i figured out that there is three overlaps in the Hind3 and EcoR1 at the 21200 and the 350 mark and the 2700 mark. that means it was cut twice? but after that i dont know where to go.