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Major Diseases of a Century Ago
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In the 1950s, 20,000 cases of polio occurred annually. After vaccination began, the number of cases plummeted to 10 in 1979. The major diseases of a century ago reflect how far we have come in our scientific and medical knowledge. Since then, the landscape of human health has evolved significantly, shaped by advancements in science, medicine, and technology. In this article, we will journey through time to understand the major diseases humans faced a hundred years ago. Infectious DiseasesOne hundred years ago, infectious diseases were among the leading causes of death. These diseases were caused by pathogens such as bacteria, viruses, and parasites. Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, was a major global heal ...
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4275 |
bio_man |
6 months ago |
Strange disease that causes fibers to grow underneath the skin
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Imagine a disease whose presence is marked by a feeling of something crawling along your skin, stinging every part of your body as if there is insect or parasite infestation that doesn't go away. Not only that, but your skin is plagued with the presence of multicolored filaments that lie under, are embedded in, or project from skin. Morgellons disease (pronounced with either a hard or soft "g") is a highly misunderstood skin condition that was first reported in the USA in 2002, although may have a longer history depending on where you look. The characteristic filaments described earlier are microscopic, visually resembling textile fibers, and are white, black, or a more vibrant color, such as red or blue (left image). In addition to fiber p ...
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3750 |
bio_man |
A year ago |
Drug-resistant bacteria are no match for this newly discovered compound
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Researchers have discovered a new compound, named 'darwinolide', inside an Antarctic sponge, Dendrilla membranosa (above, middle), that has shown to kill 98.4 percent of methicillin-resistant Staphylococcus aureus (MRSA) cells it comes in contact with. Lab tests so far suggest that it has a unique structure that allows it to penetrate the 'biofilm' that MRSA throws up to protect itself from treatments. The next step is to synthesise darwinolide in the lab, so they don't have to rely on extracting it from live Antarctic sponges. If the researchers are able to show that they can use darwinolide to fight MRSA in a clinical setting, it could save the lives of tens of thousands of people every years. Source: http://pubs.acs.org/doi/abs/10.1021/ac ...
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4055 |
bio_man |
7 years ago |
Gut bacteria affects mood and brain function in mice
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According to a study published in the medical journal eLife, researchers found that specific combinations of gut bacteria produce substances that affect myelin content and cause social avoidance behaviors in mice. Researchers transferred fecal bacteria from the gut of depressed mice to genetically distinct mice exhibiting non-depressed behavior. The study showed that the transfer of microbiota was sufficient to induce social withdrawal behaviors and change the expression of myelin genes and myelin content in the brains of the recipient mice. In an effort to define the mechanism of gut-brain communication, researchers identified bacterial communities associated with increased levels of cresol, a substance that has the ability to pass the bloo ...
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3893 |
duddy |
7 years ago |
Bacteria spray gun
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In the reproductive tract of the Hawaiian bobtail squid, there is a mysterious gland that releases bacteria that protect the squid’s eggs from fungus. When researchers applied antibiotics to freshly-laid squid eggs, fuzzy fungus soon moved in, smothering the eggs of the gemlike creatures. For more information, visit: http://www.nap.edu/read/13500/chapter/2#15 ...
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18240 |
duddy |
8 years ago |
Watch these white blood cells destroy this roundworm
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White bloods cells, known scientifically as leukocytes, are immune system cells that fight infect. The immune system is made up of a network of cells, tissues, and organs that work together to protect the body. Sometimes our bodies encounter pathogens like bacteria, or in this case a parasitic worm. Roundworms, or nematodes, are parasites that can infect people by living and feeding in the intestines. There are different kinds of worms that can cause infection, and they can range in length from 1 millimeter to 1 meter. Luckily, this worm was no challenge for these hungry white blood cells. ...
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5081 |
duddy |
8 years ago |
Speedy bacteria
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Bdellovibrio bacteriovorus is a bacterium that attacks other bacteria. It can charge its prey at speeds of up to 100 micrometers per second, comparable to a human running 600 kilometers per hour. It then bores into its hapless victim by spinning at 100 revolutions per second. Most bacteria aren't quite that fast, but they can move by whipping flagella or by spiraling through their environment. ...
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14244 |
duddy |
8 years ago |
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2614 |
duddy |
8 years ago |
Try dates, not honey
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While they are super sweet, syrup made from this ancient fruit has antibacterial compounds that are more effective than honey. In case you've never had it or seen it before, dates are a thick, dark brown, and super-sweet fruit used in Middle Eastern cuisine. New research suggests that date syrup contains chemical compounds that help ward off a number of bacterial infections, including those caused by Staphylococcus aureus and Escherichia coli. This was discovered after scientists inhibited the growth of these pathogens for about six hours, which researchers say is faster than manuka honey - a honey known for its antibacterial and wound healing properties. ...
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29862 |
duddy |
8 years ago |
Attention paleo dieters
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A new study suggests that humans who live in industrialized societies don’t have the guts to stomach a real hunter-gatherer diet. Compared with hunter-gatherers, industrialized peoples’ intestines have fewer kinds of microbes - and are missing at least one major group of ancient bacteria.
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51539 |
duddy |
9 years ago |
You may think you know yourself, but this video will change everything
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As a secondary school educator, I often see students sharing their drinks with one another. This bugs me more than anything because it causes germs to be easily spread from one person to another. The problem is, students have this misconception that if they are not sick, then the person they are sharing their drink with won't get sick either. Sounds rational, but is it true? Definitely not. Each person's immune system is unique, and so is our microbiome (as described in the video below). What may be harmless to one person may not be so much to another. I believe this video does an excellent job demonstrating that not only are humans unique in a sense that we each have our own personalities, have different occupations, and come from differe ...
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10016 |
duddy |
9 years ago |
Good bacteria helps to defend your brain
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The microbes that live in your body outnumber your cells 10 to one. Recent studies suggest these tiny organisms help us digest food and maintain our immune system. Now, researchers have discovered yet another way microbes keep us healthy: They are needed for closing the blood-brain barrier, a molecular fence that shuts out pathogens and molecules that could harm the brain.
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6126 |
duddy |
9 years ago |
Quite possibly the world's most resistant bacteria
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Deinococcus radiodurans is an extremophilic bacterium, one of the most radiation-resistant organisms known. It can survive cold, dehydration, vacuum, and acid, and is therefore known as a polyextremophile and has been listed as the world's toughest bacterium in The Guinness Book Of World Records.
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5091 |
duddy |
9 years ago |
Peanut allergies could be a thing of the past
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New research from the University of Chicago in the US shows that a class of bacteria known as Clostridia can block peanut allergies in mice, and suggests it could be used to treat similar conditions in humans. Clostridia is one of the types of bacteria killed off by antibiotic use in early childhood, and this research supports the emerging theory that increased antibiotic use is one of the factors that has caused food allergies in kids to rise by 50% since 1997. Source: http://www.sciencealert.com.au/news/20142708-26075.html ...
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6254 |
duddy |
9 years ago |
Here's what you get when you swallow seawater
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This is a single drop of seawater, magnified 25 times. The amazing image shows bacteria, worms, fish eggs, crab larva, diatoms, and much more. Think about THAT next time you swallow a mouthful of seawater.
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2760 |
duddy |
9 years ago |
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2097 |
ehd123 |
10 years ago |
World's cleanest bacteria
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A bacterium previously unknown to science was found in two spacecraft clean rooms, one in Florida and the other in Guiana. Space agencies use these rooms to prepare spacecraft for launch and are considered two of the most sterile places on Earth.
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5727 |
duddy |
10 years ago |
World's deadliest toxin
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The deadliest substance known to man is a recently discovered type of botulinum toxin ( botox). The scientists who discovered it haven’t found an antitoxin yet, so they have decided not to publish the gene sequence due to security concerns. The toxin comes from the bacterium Clostridium botulinum and blocks the chemical signals that makes nerves work, causing botulism and death by paralysis. The image shown above is the protein structure of botulinum toxin.
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3097 |
duddy |
10 years ago |
Vulnerability to tuberculosis
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If you’re not already acquainted, meet Mycobacterium tuberculosis – a wildly successful bacterium that has marched in lockstep with our population growth and history. The cause of tuberculosis, this bacterium is said to infect a new host every single second. Research lead Caitlin Pepperell from University of Wisconsin-Madison remarked, "Evolutionary theory predicts that M. tuberculosis populations should be vulnerable to extinction. Yet it is obviously highly prevalent. It must have some incredibly clever strategies and tricks to hang on." A paper published last month in PLoS Pathogens investigated 63 genomes from the bacteria and related pathogenic mycobacteria to gain insight into how natural election pressures have shaped its evolution and ...
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3404 |
duddy |
10 years ago |
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2717 |
savio |
10 years ago |
Two new gigantic viruses
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Have you heard about two new gigantic viruses that have been discovered? They measure around 1 micrometer long & half that across – larger than some eukaryotic cells! Massive genomes up to 2.5 Mb (millions of base pairs) are present to match their giant size. Their discovery raises many questions on viral diversity that remains unexplored.
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2243 |
duddy |
10 years ago |
Bacterial growth at -15°C
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Researchers from McGill University in Montreal have discovered a bacterium living in the frozen permafrost of the high Arctic. The permafrost bacterium, Planococcus halocryophilus strain Or1, grows and divides at -15°C and can even remain metabolically active at -25°C. This bacteria is yielding clues about how extraterrestrial organisms might endure extreme conditions - as one of the things that makes it extremely hard for life to flourish in foreboding places like Mars and the moons of Saturn is the punishing cold. ...
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3681 |
duddy |
10 years ago |
Radioactive bacteria
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Listeria bacteria has been enlisted by researchers to selectively infect metastatic pancreatic cancer cells and deliver radioisotopes into them. The experimental treatment dramatically decreased the number of metastases (cancers that have spread to other parts of the body) in a mouse model of highly aggressive pancreatic cancer without harming healthy tissue. Mice livers are shown above. The saline control liver on the left presents a large number of metastases compared to the liver on the right which was subject to the radioactive Listeria treatment. ...
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3141 |
duddy |
10 years ago |
The Midas touch
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Mythical King Midas was ultimately doomed because everything he touched turned to gold. Now, the reverse has been found in bacteria that owe their survival to a natural Midas touch. Delftia acidovorans lives in sticky biofilms that form on top of gold deposits, but exposure to dissolved gold ions can kill it. That's because although metallic gold is unreactive, the ions are toxic. To protect itself, the bacterium has evolved a chemical that detoxifies gold ions by turning them into harmless gold nanoparticles. These accumulate safely outside the bacterial cells. ...
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6433 |
duddy |
11 years ago |