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A link between depression and heart disease
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For quite some time it's been known in the medical community that a link exists between depression and heart disease. For example, large epidemiological surveys typically find that 1.5 to 3 percent of the population is depressed at any given time. Among patients with heart disease, however, the rate of depression is closer to 18 percent. Similarly, about 1 in 6 people in the general population has an episode of major depression during their lifetimes, compared to about 50 percent of people with heart disease. Finally, a Canadian study revealed that of 222 patients who had suffered heart attacks, those who were depressed were four times as likely to die within the next 6 months. Amassing this evidence is one thing, but explaining it is quite ...
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1048 |
bio_man |
11 months ago |
Angiotensin-converting enzyme inhibitor
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Angiotensin-converting enzyme (ACE) inhibitors are a remarkable class of drugs for treating hypertension – high blood pressure. These drugs work by interfering with the enzymes that convert an inactive chemical known as angiotensin I to an active form, angiotensin II. Angiotensin II increases the retention of salt and water in the body, raising blood pressure. ACE inhibitors interfere with, or inhibit, the formation of angiotensin II, resulting in relaxed arterial walls and lowered blood pressure. Since the release of the first ACE inhibitor in the 1980s, known generically as captopril, there are now several different ACE inhibitors available on the market. Many of them are also available in combination with other types of hypertension medic ...
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17428 |
bio_man |
2 years ago |
How asthma is treated
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Asthma is one of those illnesses that is so common that we never stop to question what causes it and how it could be treated. Affecting more than 25 million people, asthma is one of the most common chronic respiratory conditions in the United States. It is caused by the increased reactivity of the tracheobronchial tree to various stimuli, including exercise, allergies, or infections of the respiratory tract. Symptoms include, but are not limited to breathlessness, cough, wheezing, and chest tightness. Common Triggers of Asthma The most commonly used medications for asthma are: bronchodilators, xanthine derivatives, leukotriene inhibitors, corticosteroids, and mast cell stabilizers (see full list below). Xanthine derivatives treat asthma by re ...
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3954 |
bio_man |
5 years ago |
Five Common Eye-Related Conditions and Diseases
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Try imagining for a second how it'd feel to lose your eyesight. It's almost unimaginable because your vision is perhaps the most valuable tool for survival. This is why we need to constantly protect our eyes and learn what could potentially ail them. Below is a list of five common illnesses that plague the precious eyes of people around the globe. GlaucomaGlaucoma is damage to the optic nerve, often caused by elevated intraocular pressure. It results from excessive production of aqueous humor or diminished ocular fluid outflow. Glaucoma is a leading cause of blindness, secondary to optic nerve damage. As of yet, there is no cure. Everyone is at risk, and there may be no warning signs. It is six to eight times more common in African Americans ...
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2426 |
bio_man |
5 years ago |
The possible cause for heavy periods explained
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Nearly one-third of women experience heavy periods each month. This means that unlike normal periods where women lose up to 40 mL of blood per cycle, some women lose as much as 80 mL (more than a quarter of a cup) in at least one cycle throughout their life. Scientists think they might have found the answer as to why this happens, and they are blaming it on a non-hormonal protein. A new small study suggests that low levels of a specific protein known as hypoxia-inducible factor 1 (HIF1, right) might be to blame. HIF1 is a pretty handy healing molecule. When oxygen levels drop in parts of the body, a condition known as hypoxia, HIF1 activates more than 60 genes linked to tissue regeneration, and has already been shown to play a role in repai ...
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4281 |
duddy |
7 years ago |
Living without a heart
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Stan Larkin (pictured on the right), who's now 25, was diagnosed with familial cardiomyopathy. This form of disease results in the heart having difficulty pumping enough blood through the body. Faced with a lack of compatible heart donors, Stan underwent an operation in 2014 to remove his failing heart and replace it with an external total artificial heart, dubbed the Freedom portable driver. This battery-powered device uses compressed air to pump blood around the body in the same way a heart does, and as the name suggests, it is portable and only weighs 6 kilograms (13 pounds). The device does an incredible job at keeping the patient in a healthy condition while a donor heart becomes available, but it isn’t considered a long-term option. ...
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6101 |
duddy |
7 years ago |
Heavy marijuana users produce less dopamine
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For the first time, scientists have discovered a link between heavy marijuana use and reduced dopamine production. Just so you know, dopamine is the hormone/neurotransmitter that is released during any kind of satisfaction - it's the same hormone that is released in your brain when you eat chocolate. In a recent study, lower dopamine release was found in the striatum - a region of the brain that is involved in working memory, impulsive behavior, and attention, in addition to subregions involved in associative and sensorimotor learning, and in the globus pallidus. Previous studies have shown that addiction to other drugs of abuse, such as cocaine and heroin, have similar effects on dopamine release, but such evidence for cannabis was mis ...
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4224 |
duddy |
8 years ago |
Running reduces tumor size in mice by 50%
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According to a new study published in Cell Metabolism, mice who spent their free time on a running wheel were better able to shrink tumors (a 50 percent reduction in tumor size) compared to their less active counterparts. Researchers found that the surge of adrenaline ( epinephrine) that comes with a high-intensity workout helped to move cancer-killing immune (NK) cells toward lung, liver, or skin tumors implanted into the mice. While the research is hopeful for patients looking for inexpensive ways to manage their cancer, more needs to be learned about the effects of exercise on metastasis and longevity, as well as if the observations hold true in humans. Scientists also wants to explore the combined impact of anti-cancer treatments and ex ...
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11184 |
duddy |
8 years ago |
Goat's milk, a cure for HIV?
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A medical doctor claims he has the cure for HIV, a cure so simple it's laughable. According to Dr. Samir Chachoua, the Caprine Arthritis Encephalitis Virus (CAEV) in goats milk "destroys HIV and protects people who drink it for life". The so-called researched voluntarily infected himself with Charlie Sheen's HIV-infected blood, and cured himself shortly after with this cocktail. The moral of the story is, if you are traveling across the countryside and see a goat limping, please stop and milk it for Charlie. It's the least you can do. Joking aside, here's the interview with Bill Maher. ...
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6477 |
duddy |
8 years ago |
Hair loss no more - a promising treatment for baldness
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Isn't it strange, two FDA-approved drugs - topical ruxolitinib or tofacitinib - can reawaken dormant hair follicles! According to the study, within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo). According to researchers at Columbia University Medical Center, inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth. These drugs, known as JAK inhibitors have been approved to treat blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested ...
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20470 |
duddy |
8 years ago |
This strange disease turns one's skin into bone
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Known an fibrodysplasia ossificans progressive, or FOB for short, this disease can suddenly turn a person’s tissues and muscles into bone, thereby permanently immobilizing parts of the bodies. Joints such as elbows or ankles may become frozen in place; jaw motion can be impeded and the rib cage fixed, making eating or even breathing difficult. Currently, no cure exists to combat this rare condition.
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7955 |
duddy |
8 years ago |
Double hand transplant
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At only eights years-old, Zion Harvey is the youngest person with a double hand transplant ever. Four teams of surgeons worked over 11 hours to complete the complicated operation. Zion lost both of his hands and feet when he contracted sepsis at age two and experienced multiple organ failures. When he was four, he received a kidney transplant from his mother, and leg prosthetics have enabled him to engage in many activities.
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1939 |
duddy |
8 years ago |
What do the Cubans have that the rest of the world doesn't?
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A possible vaccine for lung cancer! In a country known for cigars, lung cancer is one of the major killers in Cuba. So for the past 25 years, they’ve been developing Cimamax, which is now available freely to Cubans. According to a Phase II trial conducted in Cuba in 2008, lung cancer patients who received the vaccine lived an average of four to six months longer than those who didn’t. This led Japan and some European countries to trial the drug as well. The drug itself is far from flawless and, by attacking a cell’s protein rather than the tumour directly, can have severe side effects, including – of all things - causing a higher risk of cancer. It might not be a "cure" in the traditional sense, but it's a way of managing the disease. What t ...
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10871 |
duddy |
8 years ago |
Brain just can't catch a break
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The importance of adequate, non-distracted, deep sleep could not be emphasized enough. Recent research has put the brain yet again under the spotlight, this time only to shed some light on one more reason we should be getting our sleep and why. Make sure to watch the video above. It is hands down, one of the best TED talks I have listened to. As for now, I'mma go make my CSF flush my amyloid betas Nighty, night!
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16412 |
ehd123 |
8 years ago |
Want to get rid of your double chin, now you can without surgery
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An injectable drug, called ATX-101, currently being tested melts away "submental fat", better known as the double chin. According to its makers, ATX-101 can be injected in a clinic and takes just five minutes. It consists of deoxycholic acid, a naturally-occurring molecule that helps us break down fat, which effectively destroys the membranes of fat cells, causing them to burst and then be metabolised by the body. ...
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27568 |
duddy |
9 years ago |
New ways to stop cancer once it spreads
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When a person dies from cancer, the culprit isn't usually the original tumor - it's metastasis, the spread of cancer cells throughout the body. Now, researchers have managed to package a drug in nanoparticles (a microscopic particle with at least one dimension less than 100 nm) so that it can target these cancer cells without, crucially, interfering with normal cells - and report that they've stopped cancer cells from spreading in mice. Nanoparticle research is currently an area of intense scientific research, due to a wide variety of potential applications in biomedical, optical, and electronic fields. Source: http://news.sciencemag.org/biology/2015/01/nanoparticle-drug-stops-cancer-s-spread-mice ...
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27311 |
duddy |
9 years ago |
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17499 |
ehd123 |
9 years ago |
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10289 |
ehd123 |
9 years ago |
Cancer, could it be just bad luck?
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In a paper this week in Science, two scientists at John Hopkins have united biology and mathematics to propose a mathematical formula to explain the genesis of cancer. Take the number of cells in an organ, identify what percentage of them are long-lived stem cells, and determine how many times the stem cells divide. With every division, there’s a risk of a cancer-causing mutation in a daughter cell. Thus, Tomasetti and Vogelstein reasoned, the tissues that host the greatest number of stem cell divisions are those most vulnerable to cancer. When Tomasetti crunched the numbers and compared them with actual cancer statistics, he concluded that this theory explained two-thirds of all cancers. “Using the mathematics of evolution, you can really ...
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12521 |
ehd123 |
9 years ago |
Insights into the Hippocampus
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When Henry Molaison (now widely known as H.M.) cracked his skull in an accident, he began blacking out and having seizures. In an attempt to cure him, daredevil surgeon, Dr. William Skoville, removed H.M.'s hippocampus. Luckily, the seizures did go away — but so did his long-term memory! Sam Kean walks us through this astonishing medical case, detailing everything H.M. taught us about the brain and memory.
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14215 |
ehd123 |
9 years ago |
A scam-artist or a medical doctor?
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I've been advocating this for years. Just because you're a doctor and you're on TV, doesn't make you a know-it-all. Researchers from the University of Alberta have found that half the advice on Dr. Oz is wrong or has no evidence to back it up. In fact, on average, the shows give their viewers around 12 different recommendations per episode. But only half of them are supported by research. Just comes to show that people will believe anything they see on TV. When there is money to be made and an agenda to be pushed, lies will follow. ...
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17556 |
duddy |
9 years ago |
Apparently Ibuprofen helps you live longer - not my words
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Good news for pain-pill poppers: Ibuprofen (found in Advil) may help you live longer. A new study shows that it increases life span in lab organisms, raising the possibility it does the same thing in people. To put ibuprofen through its paces, biochemist Michael Polymenis of Texas A&M University, College Station, and colleagues gave yeast, nematode worms, and fruit flies doses of the drug that are comparable to what humans would take. The life spans of all three types of organisms increased if they received ibuprofen, the researchers report today in PLOS Genetics. In yeast, for instance, ibuprofen stretched life span by 17%, half of what researchers can produce by cutting the cells’ food supply (another approach to increasing longevity). ...
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12791 |
duddy |
9 years ago |
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8126 |
duddy |
9 years ago |
Want to become a brain surgeon? Better get used to this
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Watch as a neurosurgeon opens up a patient's skull and clears the clotted blood from the surface of her brain. We probably don't have to tell you that this is extremely graphic footage, but - you've been warned.
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5415 |
duddy |
9 years ago |
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7052 |
duddy |
9 years ago |
This super-effective cancer-fighting berry can help fight cancer
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A drug made from berries produced the blushwood tree ( Hylandia dockrillii), found in Australia, has been used to treat animals with face and neck tumours, and it starts taking effect within five minutes. Human trials have now been approved. According to researchers, in 75 percent of the 300 animals cases, the tumour disappeared in individuals that were treated with isolated compound found in the seed, and has so far not come back. "The compound works in three ways essentially: it kills the tumour cells directly, it cuts off the blood supply and it also activates the body's own immune system to clean up the mess that's left behind." ...
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6247 |
duddy |
9 years ago |
Grapes kill bacteria that causes acne?
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An antioxidant derived from grapes, known as resveratrol, could work as an acne treatment by inhibiting bacteria growth. Researchers have found that combining acne medication with the antioxidant makes the drug more effective. Now you may apply grapes on your face ...
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5552 |
duddy |
9 years ago |
This is how doctors used to figure out if a woman was pregnant
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How did doctors figure out if women were pregnant back in the day? They used frogs, of course! Before the 1960's, the only reliable pregnancy test involved injecting a woman's urine into an African clawed frog and seeing if the frog spawned. This peculiar method, known as the ' frog pregnancy test,' may sound bizarre today, but it was a common practice in the early to mid-20th century. The African clawed frog, a species native to sub-Saharan Africa, was preferred for this test because of its unique reproductive system. If a woman was pregnant, her urine would contain hormones that would induce the frog to lay eggs, confirming the pregnancy. While this method may seem unusual by modern standards, it was an early example of using biological indi ...
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1454 |
duddy |
9 years ago |
Peanut allergies could be a thing of the past
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New research from the University of Chicago in the US shows that a class of bacteria known as Clostridia can block peanut allergies in mice, and suggests it could be used to treat similar conditions in humans. Clostridia is one of the types of bacteria killed off by antibiotic use in early childhood, and this research supports the emerging theory that increased antibiotic use is one of the factors that has caused food allergies in kids to rise by 50% since 1997. Source: http://www.sciencealert.com.au/news/20142708-26075.html ...
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6263 |
duddy |
9 years ago |
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6504 |
duddy |
9 years ago |
The descent into Alzheimer's disease
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A doctor chronicles the signatures of his patient as the disease took hold of her. Our love goes out to anyone who's dealt with this awful disease in some way.
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1 |
11205 |
duddy |
9 years ago |
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5792 |
duddy |
9 years ago |
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1 |
5955 |
duddy |
9 years ago |
Can this sea snail cure herpes?
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Australian scientists are creating a new herpes-blocking drug using a protein found in the blood of abalones. If successful, it could prevent the virus from entering human cells, thereby prevent future outbreaks of cold sores.
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4332 |
duddy |
9 years ago |
Aspiring doctors, this phone is for you
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Say hello to the Blackberry Passport. This killer phone sports a huge 4.5 inch 1440x1440 LCD display, massive 3450 mAH battery, and a capacitive touch keyboard. According to its makers, the phone's resolution is perfect for seeing images accurately, and any doctor who wants to look at detailed x-rays on their smartphone couldn’t do any better than the device’s 4.5-inch screen.
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4136 |
duddy |
9 years ago |
One of the most caring professions
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Doctors bow in reverence to cancer victim, Liang Yaoyi, in China. Nine-year-old Liang died from a brain tumour and donated his organs because, "There are many people doing great things in the world. I want to be a great kid too." What an incredible person.
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1161 |
duddy |
9 years ago |
Helping the paralysed walk again
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Great news! ReWalk, a motorised exoskeleton suit that helps people who are paralysed from the waist down to stand up and walk again, has been approved for personal use.
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7647 |
duddy |
9 years ago |
How do you stitch an eyeball?
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This is what eyeball stitches look like after a cornea transplant. Beautiful and terrifying all at once.
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3539 |
duddy |
9 years ago |
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2878 |
duddy |
10 years ago |
Surgeons successfully replaces a patient's skull with 3D-printed version
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Surgeons have successfully replaced a patient’s skull with a 3D-printed version. Three months after the operation the patient, a 22-year-old woman with a rare disorder that thickened her skull and gave her poor eyesight as well as headaches, has recovered her eyesight and has gone back to work. ...
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3168 |
duddy |
10 years ago |
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2915 |
duddy |
10 years ago |
C-section on a turtle?
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Surgeons performed a C-section on this turtle and saved her life! A turtle named Dabao was a bit lethargic and zookeepers at China’s Chengu City Zoo thought she was sick and sent her for x-rays. The results were surprising: 14 eggs were stuck in the birth canal. To make sure Dabao survived, the surgeons opened the shell with a skull opener, carefully removed the 14 eggs (which were immediately buried in sand to await hatching) and resealed the shell with epoxy resin.
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2918 |
duddy |
10 years ago |
This tiny camera takes 3D images of your innards
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This tiny camera invented by scientists F. Levent Degertekin can provide high-definition 3D images of your arteries. The camera, which is the size of an uncooked quinoa grain, uses ultrasound imaging techniques to capture what going on inside the body. The images produced can be used in the surgical theatre, giving doctors a direct view of obstructions in a blood vessel.
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1 |
2884 |
duddy |
10 years ago |
The end of baldness
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In a world’s first researchers have converted adult cells into stem cells that regenerated into different cell types of human skin and hair follicles. The follicles produced hair shaft and could be used for hair regeneration. Is this the end of baldness?
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3193 |
duddy |
10 years ago |
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8611 |
duddy |
10 years ago |
World's deadliest toxin
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The deadliest substance known to man is a recently discovered type of botulinum toxin ( botox). The scientists who discovered it haven’t found an antitoxin yet, so they have decided not to publish the gene sequence due to security concerns. The toxin comes from the bacterium Clostridium botulinum and blocks the chemical signals that makes nerves work, causing botulism and death by paralysis. The image shown above is the protein structure of botulinum toxin.
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3097 |
duddy |
10 years ago |
Think you're having a bad hair day, check this out
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Uncombable hair syndrome, also known as Pili trianguli et canaliculi, is a rare structural anomaly of the hair with a variable degree of effect. It was first reported in the early 20 th century and was described in the 1970s. It becomes apparent from as little as 3 months to up to 12 years. The hair is normal in quantity and is usually silvery-blond or straw-colored. It is disorderly, it stands out from the scalp, and cannot be combed flat. The underlying structural anomaly is longitudinal grooving of the hair shaft, which appears triangular in cross section. There usually is no family history, though the characteristic hair shaft anomaly can be demonstrated in asymptomatic family members by scanning electron microscopy. To be noticeable, 50% ...
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4495 |
duddy |
10 years ago |
Brain defects go a long way
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This is a human brain without grooves and folds, a condition known as lissencephaly. It belonged to a patient who died in a mental health facility in 1970, and almost a year ago a photographer found the jar containing the brain in a collection at the University of Texas, Austin. People with this rare condition suffer from seizures, muscle spasms, a range of learning difficulties, and usually die before the age of ten. ...
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5185 |
duddy |
10 years ago |
The strangest medical story ever
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This 22-year-old man had a car accident last year and as a result his nose became infected and deformed. Doctors weren’t able to repair it, but decided to take cartilage from one of the young man’s ribs to grown a new nose. The nose, which is temporarily attached to his forehead, has been developing for 9 months and is ready to be transplanted.
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5044 |
duddy |
10 years ago |
The road to a cure for HIV
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A new vaccine has successfully killed the simian immunodeficiency virus (SIV) that causes AIDS in monkeys. It's hoped that with further research, an HIV-form of the vaccine can soon be tested in humans.
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3098 |
savio |
10 years ago |
Would you like to try a gluten-free diet or a helminth?
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Parasitologist espouses using parasitic worms for treatment of autoimmune diseases – Dr. Joel Weinstock, at Tufts Medical Center in a commentary piece published in the journal Nature, describes work that he and colleagues have been involved in that focuses on studying the possibility of introducing parasitic worms into the guts of patients suffering from autoimmune diseases such as Crohn's disease. The thinking he says, is that modern hygienic lifestyles may be contributing to such diseases and that reintroducing parasitic worms and perhaps certain bacteria into the gut may restore a natural balance in the gut and relieve patients of such symptoms as chronic diarrhea, bleeding and infections. Source: http://medicalxpress.com/news/2012-11-p ...
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3480 |
duddy |
10 years ago |
Pellagra
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In the early 1900s, the disease pellagra was widespread in the United States, especially in southern states. Individuals with pellagra were weak, and they developed diarrhea, a skin rash, and mental confusion. Each year, thousands of Americans died from this dreaded illness. In 1914 the U.S. surgeon general assigned Joseph Goldberger, a physician who worked in a federal government laboratory, to study pellagra. Most medical experts thought pellagra was an infectious disease because it often occurred where people lived in close quarters, such as prisons, orphanages, and mental health institutions. Goldberger knew from his previous research that infectious diseases usually spread through a population by close physical contact. While investiga ...
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2808 |
savio |
10 years ago |
Baby blue eyes
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Waardenburg Syndrome is a rare autosomal genetic disorder that has possible bright blue eyes as one of its qualifying criteria, along with possible deafness (common). Actually, the cause of the blue eyes is a form of albinism that may include patches of non-pigmented skin or forehead hair, regardless of ethnicity. There are four types of Waardenburg Syndrome, with a mix of possible characteristics as the determinant. Medical challenges increase with type. The boy in the picture is displaying two major symptoms of type 1; bright blue eyes and dystopia canthorum, a condition where the inner corners of the eyes are set more widely apart, but with normally distanced eyes. ...
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3950 |
savio |
10 years ago |
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2211 |
duddy |
10 years ago |
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3327 |
duddy |
10 years ago |
Potential treatment for Down's syndrome?
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Down syndrome is caused by a triple copy of chromosome 21, which leads to a number of cognitive and physical delays. Now researchers from the Sanford-Burnham Medical Research Institute in La Jolla, California, have found a protein that restores the some of the cognitive and behavioral disorders found in the disease. Mice who were deficient in the SNX27 protein exhibited similar characteristics to mice with Down syndrome—namely, they had fewer glutamate receptors, which are important for learning and memory, the team reported in Nature Medicine on Sunday (March 24). The researchers also showed that in mice with Down syndrome, the protein is blocked by a molecule encoded on chromosome 21, and produced in excess in Down syndrome mice as a re ...
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5616 |
bio_man |
11 years ago |
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3341 |
duddy |
11 years ago |
What would happen if you didn't get stitches?
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I have a big scar on my leg from when I was a kid. I often wonder what would have happened if we let it heal on its own without using stitches. Here's what happens when you do get stitches: Here's what happens without stitches: And finally, this scenario often leads to contamination. In this case, you'd get this: ...
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6578 |
duddy |
11 years ago |