Biochemistry

The cavity in the GroEL-GroES complex from E. coli provides a favorable environment that prevents ...

The cavity in the GroEL-GroES complex from E. coli provides a favorable environment that prevents ...

The cavity in the GroEL-GroES complex from E. coli provides a favorable environment that prevents ________ and mis-folding.

3493954   91   1 Reply

Nyntti

Proteins have an asymmetrical tertiary structure, while multisubunit proteins can exhibit several ...

Proteins have an asymmetrical tertiary structure, while multisubunit proteins can exhibit several ...

Proteins have an asymmetrical tertiary structure, while multisubunit proteins can exhibit several types of symmetry.
T/F?

3493954   114   1 Reply

Nyntti

________ spectroscopy can be used to study dynamic processes in solution.

________ spectroscopy can be used to study dynamic processes in solution.

________ spectroscopy can be used to study dynamic processes in solution.

3493954   83   1 Reply

Nyntti

The specific interaction between an antibody and antigen occurs by virtue of both shape and ________ ...

The specific interaction between an antibody and antigen occurs by virtue of both shape and ________ ...

The specific interaction between an antibody and antigen occurs by virtue of both shape and ________ complementarity.

3493954   104   1 Reply

Nyntti

Which of the following statements is FALSE?

Which of the following statements is FALSE?

Which of the following statements is FALSE?
A) Myoglobin is a single polypeptide chain folded about a heme prosthetic group.
B) Hemoglobin is a tetramer, each of which binds a heme group.
C) In both hemoglobin and myoglobin, iron is ch

3493954   81   1 Reply

BurgaskO

The production of carbon dioxide during respiration in aerobic tissues lowers the pH in ...

The production of carbon dioxide during respiration in aerobic tissues lowers the pH in ...

The production of carbon dioxide during respiration in aerobic tissues lowers the pH in erythrocytes, which in turn ________ the affinity of oxygen binding to hemoglobin.

3493954   87   1 Reply

BurgaskO

F-actin is a polymer of G-actin monomers and exhibits symmetry.T/F?

F-actin is a polymer of G-actin monomers and exhibits symmetry.T/F?

F-actin is a polymer of G-actin monomers and exhibits symmetry.
T/F?

3493954   110   1 Reply

Nyntti

Calcium regulates muscle contraction by binding to:

Calcium regulates muscle contraction by binding to:

Calcium regulates muscle contraction by binding to:
A) actin.
B) myosin.
C) tropomyosin.
D) troponin C.
E) troponin T.

3493954   96   1 Reply

BurgaskO

The greatest conformational change in the neck piece of myosin occurs during ATP hydrolysis.T/F?

The greatest conformational change in the neck piece of myosin occurs during ATP hydrolysis.T/F?

The greatest conformational change in the neck piece of myosin occurs during ATP hydrolysis.
T/F?

3493954   75   1 Reply

Nyntti

Which of the following statement is FALSE?

Which of the following statement is FALSE?

Which of the following statement is FALSE?
A) The free energy barrier in a chemical reaction must be overcome in order for products to form.
B) An increase in temperature can result in an increased reaction rate.
C) Lowering the free e

3493954   76   1 Reply

BurgaskO

In a favorable reaction the free energy of the products is ________ than the free energy of the ...

In a favorable reaction the free energy of the products is ________ than the free energy of the ...

In a favorable reaction the free energy of the products is ________ than the free energy of the reactants.

3493954   105   1 Reply

BurgaskO

Pyruvate carboxylase is an example of the ligase class of enzymes.T/F?

Pyruvate carboxylase is an example of the ligase class of enzymes.T/F?

Pyruvate carboxylase is an example of the ligase class of enzymes.
T/F?

3493954   84   1 Reply

Nyntti

Non-catalyzed biochemical reactions always occur at physiological useful timescales.T/F?

Non-catalyzed biochemical reactions always occur at physiological useful timescales.T/F?

Non-catalyzed biochemical reactions always occur at physiological useful timescales.
T/F?

3493954   62   1 Reply

Nyntti

A second-order reaction: (Multiple Choice)

A second-order reaction: (Multiple Choice)

A second-order reaction:
A) occurs when one substrate is converted into one product.
B) is characterized by two molecules coming together to form a product.
C) is the rate-limiting step of a reaction.
D) has a rate constant with u

3493954   70   1 Reply

Nyntti

Enzymes can accelerate reactions by:

Enzymes can accelerate reactions by:

Enzymes can accelerate reactions by:
A) binding a substrate or substrates.
B) promoting the removal or addition of protons.
C) correctly positioning a metal ion for catalysis.
D) lowering the energy for activation.
E) all of

3493954   112   1 Reply

BurgaskO

The equilibrium state of a biochemical reaction is approached ________ in the presence of a ...

The equilibrium state of a biochemical reaction is approached ________ in the presence of a ...

The equilibrium state of a biochemical reaction is approached ________ in the presence of a catalyst.

3493954   110   1 Reply

BurgaskO

The lock and key model of substrate binding and enzymatic catalysis explains:

The lock and key model of substrate binding and enzymatic catalysis explains:

The lock and key model of substrate binding and enzymatic catalysis explains:
A) the release of product.
B) substrate specificity.
C) formation of a transition state.
D) the catalytic mechanism.
E) structural changes that occ

3493954   70   1 Reply

BurgaskO

Which of the following amino acid residues are often involved in proton transfers in ...

Which of the following amino acid residues are often involved in proton transfers in ...

Which of the following amino acid residues are often involved in proton transfers in enzyme-catalyzed reactions?
A) Histidine, aspartate, serine, and cysteine
B) Serine, tyrosine, arginine, and cysteine
C) Glutamine, asparagine, lysine

3493954   82   1 Reply

BurgaskO

The ________ hypothesis suggests that an enzyme can induce distortion of the substrate or the ...

The ________ hypothesis suggests that an enzyme can induce distortion of the substrate or the ...

The ________ hypothesis suggests that an enzyme can induce distortion of the substrate or the substrate can induce conformational changes in the enzyme that stabilize the transition state.

3493954   97   1 Reply

Nyntti

The formation of an enzyme-substrate complex tends to be thermodynamically favorable due to ________ ...

The formation of an enzyme-substrate complex tends to be thermodynamically favorable due to ________ ...

The formation of an enzyme-substrate complex tends to be thermodynamically favorable due to ________ interactions between the substrate and enzyme.

3493954   125   1 Reply

BurgaskO

The cofactor NAD+ is: (Multiple Choice)

The cofactor NAD+ is: (Multiple Choice)

The cofactor NAD+ is:
A) a reductant.
B) an oxidant.
C) oxidized to NADH/H+ in dehydrogenase reactions.
D) able to accept 2 electrons and 2 protons.
E) covalently linked to enzymes in whose catalytic activity it assists.

3493954   120   1 Reply

Nyntti

Coenzymes or cofactors are irreversibly changed during catalysis.T/F?

Coenzymes or cofactors are irreversibly changed during catalysis.T/F?

Coenzymes or cofactors are irreversibly changed during catalysis.
T/F?

3493954   109   1 Reply

BurgaskO

Metal ions are often required for catalytic efficiency but they may not remain permanently bound to ...

Metal ions are often required for catalytic efficiency but they may not remain permanently bound to ...

Metal ions are often required for catalytic efficiency but they may not remain permanently bound to the protein or take part in the catalytic process.
T/F?

3493954   53   1 Reply

Nyntti

A mutation causing an amino acid change in an enzyme that affects the turnover number kcat will ...

A mutation causing an amino acid change in an enzyme that affects the turnover number kcat will ...

A mutation causing an amino acid change in an enzyme that affects the turnover number kcat will always affect the KM as well.
T/F?

3493954   108   1 Reply

Nyntti

Which of the following statements about inhibitors of enzyme-catalyzed reactions is TRUE?

Which of the following statements about inhibitors of enzyme-catalyzed reactions is TRUE?

Which of the following statements about inhibitors of enzyme-catalyzed reactions is TRUE?
A) An uncompetitive inhibitor typically affects KM but not kcat.
B) A competitive inhibitor does not affect Vmax.
C) An uncompetitive inhibitor w

3493954   63   1 Reply

BurgaskO

A reversible ________ inhibitor is one that binds to the active site of an enzyme but cannot undergo ...

A reversible ________ inhibitor is one that binds to the active site of an enzyme but cannot undergo ...

A reversible ________ inhibitor is one that binds to the active site of an enzyme but cannot undergo the chemical conversion step of the reaction.

3493954   105   1 Reply

Nyntti

Which of the following is NOT a feature of substrate-level enzyme regulation?

Which of the following is NOT a feature of substrate-level enzyme regulation?

Which of the following is NOT a feature of substrate-level enzyme regulation?
A) A high substrate concentration will speed up the rate of reaction.
B) A high product concentration will slow the rate of reaction.
C) The product can be a

3493954   84   1 Reply

BurgaskO

Almost all irreversible enzyme inhibitors bind noncovalently to the enzyme.T/F?

Almost all irreversible enzyme inhibitors bind noncovalently to the enzyme.T/F?

Almost all irreversible enzyme inhibitors bind noncovalently to the enzyme.
T/F?

3493954   108   1 Reply

BurgaskO

Covalent modification can either activate or inhibit enzymes.T/F?

Covalent modification can either activate or inhibit enzymes.T/F?

Covalent modification can either activate or inhibit enzymes.
T/F?

3493954   56   1 Reply

BurgaskO

Protein kinases add a phosphoryl group to the —OH group of a ________, ________, or ________ ...

Protein kinases add a phosphoryl group to the —OH group of a ________, ________, or ________ ...

Protein kinases add a phosphoryl group to the —OH group of a ________, ________, or ________ residue of the target protein.

3493954   54   1 Reply

BurgaskO

Catalytically inactive enzyme precursors are called ________.

Catalytically inactive enzyme precursors are called ________.

Catalytically inactive enzyme precursors are called ________.

3493954   160   1 Reply

Nyntti

A stopped-flow apparatus is used to measure rates of pre-steady state slow enzymatic reactions. T/F?

A stopped-flow apparatus is used to measure rates of pre-steady state slow enzymatic reactions. T/F?

A stopped-flow apparatus is used to measure rates of pre-steady state slow enzymatic reactions.
T/F?

3493954   75   1 Reply

BurgaskO

Carbohydrates are components of the following:

Carbohydrates are components of the following:

Carbohydrates are components of the following:
A) the membrane of red blood cells.
B) nucleic acids.
C) the hormone erythropoietin.
D) the bacterial cell wall.
E) all of the above.

3493954   53   1 Reply

BurgaskO

Which of the following is an example of a monosaccharide?

Which of the following is an example of a monosaccharide?

Which of the following is an example of a monosaccharide?
A) Galactose
B) Lactose
C) Amylose
D) Maltose
E) None of the above

3493954   71   1 Reply

BurgaskO

Which of the following is considered to be the smallest carbohydrate?

Which of the following is considered to be the smallest carbohydrate?

Which of the following is considered to be the smallest carbohydrate?
A) Glucose
B) Dihydroxyacetone
C) Ribose
D) Xylose
E) Formaldehyde

3493954   51   1 Reply

BurgaskO

Amylose and amylopectin are the principle storage polysaccharides of:

Amylose and amylopectin are the principle storage polysaccharides of:

Amylose and amylopectin are the principle storage polysaccharides of:
A) bacteria.
B) plants.
C) animals.
D) mollusks.
E) insects.

3493954   248   1 Reply

Nyntti

The storage polysaccharides are ________ in plants and ________ in animals.

The storage polysaccharides are ________ in plants and ________ in animals.

The storage polysaccharides are ________ in plants and ________ in animals.

3493954   75   1 Reply

BurgaskO

Heparin is a highly sulphated glycosaminoglycan that act as an ________.

Heparin is a highly sulphated glycosaminoglycan that act as an ________.

Heparin is a highly sulphated glycosaminoglycan that act as an ________.

3493954   57   1 Reply

Nyntti

Saturated fatty acids are different to unsaturated fatty acids because they:

Saturated fatty acids are different to unsaturated fatty acids because they:

Saturated fatty acids are different to unsaturated fatty acids because they:
A) have an even number of carbon atoms.
B) have short hydrophobic tails.
C) have no C=C double bonds.
D) exhibit free rotation about the carbon carbon bo

3493954   102   1 Reply

BurgaskO

Linolenic acid has cis double bonds with the formula CH3CH2CH=CHCH2CH=CHCH2CH=CH(CH2)7COOH. Write ...

Linolenic acid has cis double bonds with the formula CH3CH2CH=CHCH2CH=CHCH2CH=CH(CH2)7COOH. Write ...

Linolenic acid has cis double bonds with the formula CH3CH2CH=CHCH2CH=CHCH2CH=CH(CH2)7COOH. Write out the abbreviated systematic numbering for this fatty acid.

3493954   306   2 Replies

throwingawayfoh