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during initation, how does initiator tRNA carry a ribosomal subunit to the mRNA?

daveed12

wrote...

Posts: 24

Rep:

12 years ago

during initation, how does initiator tRNA carry a ribosomal subunit to the mRNA?

how does initiator tRNA carry the small ribosomal subunit to mRNA if it has only two attachment sites?

my bio book says that an "initiator tRNA binds a small ribosomal subunit." but how can this be possible if tRNA only has two attachment sites: one for its anticodon, and the other for its specific amino acid.

does initiator tRNA bring small and large ribosomal subunits to mRNA or do they just know to go there?

please help, its confusing!

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juliasarands

wrote...

#1

12 years ago

Initiation: When a small subunit of a ribosome charged with a tRNA+the amino acid methionine encounters an mRNA, it attaches and starts to scan for a start signal. When it finds the start sequence AUG, the codon (triplet) for the amino acid methionine, the large subunit joins the small one to form a complete ribosome and the protein synthesis is initiated.

NB. The small ribosomal subunit recognises the whole tRNA-methionine complex rather than binding to a specific part of the tRNA.

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