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How does each SNP affect the targeting and processing of the insulin precursor protein?
Recall that under normal circumstances, the insulin precursor protein is processed in the lumen of the ER to produce the mature (functional) insulin protein. Depending on the type of mutation produced and the protein domain affected, a SNP may have a profound effect on the structure and function of the mature insulin protein, or it may have no effect on the mature protein at all.
In this exercise, you will use what you learned in the previous part to predict which domains will be present in the mature insulin protein produced by each patient. In addition, you will predict whether the insulin produced by each patient will function normally or whether the patient will exhibit some form of diabetes. For this exercise, assume that all patients are homozygous for the SNP.
Drag blue labels to blue targets and pink labels to pink targets. Labels may be used once, more than once, or not at all. For help getting started, open the Hints.

Please Help!! Attached is from the previous part
Post Merge: 4 years ago

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By looking at the diagram one is able to conclude the following:

Patient 1: B Chain
Patient 2: C Peptide
Patient 3: Diabetic Site
Patient 4: A Chain
Keweiyu,  SallyBel28,  boohaha,  kkalie,  wvf330
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Thank you! Helped a lot
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Edited: 4 years ago, StevenChan
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This Question is really difficult for me
Post Merge: 4 years ago

Well...

B chain is A+B

C peptide A+B

dibasic should be A+B+C, diabetic

The teacher explained the answer already...but too late for me, I answered it wrongly...
xeroaccuracy,  willymiami,  albotmccoy,  mads123,  GoalMachine7,  athrasher,  kas27,  biology48,  wvf330
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Thanks helped a lot.
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