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Home Q & A Board Biology-Related Homework Help Cell Biology
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heidirochelle98 heidirochelle98
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6 years ago
Acetylcholine acts at a GPCR on heart muscle to make the heart beat more slowly.
 
  It does so by ultimately opening K+ channels in the plasma membrane (as diagrammed in Figure Q16-32), which decreases the cell's excitability by making it harder to depolarize the plasma membrane.
 
  Indicate whether each of the following conditions would increase or decrease the effect of acetylcholine.
  A. addition of a drug that stimulates the GTPase activity of the G subunit
  B. mutations in the K+ channel that keep it closed all the time
  C. modification of the G subunit by cholera toxin
  D. a mutation that decreases the affinity of the  complex of the G protein for the K+ channel
  E. a mutation in the acetylcholine receptor that prevents its localization on the cell surface
  F. adding acetylcholinesterase to the external environment of the cell
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achurchachurch
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heidirochelle98 Author
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6 years ago
Thanks
cipcal
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This site is awesome
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