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phily3 phily3
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6 years ago
Using genetic engineering techniques, which of the following would you do to a protein that normally is constitutively secreted to make it accumulate in the ER?
 
  A) fuse it to GFP
  B) add an amino acid that would get a mannose-6-phosphate group added to its carbohydrate
  C) add a KDEL sequence near its C-terminus
  D) mutate one of the asparagines that is normally glycosylated to an alanine, which is not glycosylated
  E) None of these would cause the protein to accumulate in the ER.
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hellokristi4hellokristi4
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6 years ago
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phily3 Author
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6 years ago
Thank you, thank you, thank you!
wrote...

Yesterday
Good timing, thanks!
wrote...

2 hours ago
Smart ... Thanks!
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