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How is cancer chemotherapy related to purine biosyntheis?

sophie0209

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6 years ago

How is cancer chemotherapy related to purine biosyntheis?

How is cancer chemotherapy related to purine biosyntheis?
a. rapidly dividing cells require more purine biosynthesis and some chemotherapy drugs inhibit a key enzyme in purine biosynthesis
b. aminopterin is a good chemotherapy drug because it inhibits aspartate transcarbamoylase
c. cancer cells lack folic acid, and chemotherapy drugs like sulfanamide act by overproducing folic acid, which is then poisonous to the cancer cells
d. none of these

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jianhong9991

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