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Home Q & A Board Biology-Related Homework Help General Biology
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JOJO JOJO
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12 years ago
What is a central dogma of molecular biology?
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#1
Staff Member
12 years ago
DNA to RNA to Protein Slight Smile
- Master of Science in Biology
- Bachelor of Science
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#2
12 years ago
The central dogma says that you begin with DNA, which is transcribed to RNA, which is then translated into proteins (amino acids).
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#3
12 years ago
The central dogma of molecular biology states that biological information flows in only one direction, from DNA to RNA to proteins.

Francis Crick (of DNA double helix fame) coined the term without knowing what the term "dogma" meant.

Exceptions have since been found; for example, reverse transcriptase is an enzyme that uses RNA as a template to form DNA --- so information flows in the wrong direction (from RNA to DNA).
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#4
12 years ago
The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid.

In other words, the process of producing proteins is irreversible: a protein cannot be used to create DNA.
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#5
12 years ago
Information flow in the cell is unidirectional, from DNA to RNA to protein.
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