Basal Lamina of the Kidney

The basal lamina of the kidney glomerulus is a thick porous structure that acts as a filter to control the movement os solutes into urine. Ut selectively allows solutes to pass through based on their charge, shape, and size. Positively charged and neutral solutes pass through the basal lamina more easily than negatively charged ones.

a. What component and property of the basal lamina do you think contributes to this charge selectivity?

b. The ability of a matrix to selectivity filter molecules based on size and shape is a concept in biology that has been exploited by scientists to separate macromolecules in lab. Name one technique that uses this concept. What material in this technique makes up the matrix.