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Twatson22 Twatson22
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6 years ago
How can the banding patterns on Drosophila polytene chromosomes be used to aid deletion mapping of genes on the chromosomes?
 
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6 years ago
The unexpected expression of a recessive trait caused by pseudodominance (the loss of a dominant allele) can be correlated with changes in band number and physical appearance of the polytene chromosomes. For example, in a polytene X bearing wild-type alleles, deletions in certain regions can be visually observed. These can be correlated with the appearance of pseudodominant phenotypes for those alleles. The alleles can then be mapped to those missing regions on the chromosome.
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