Why is it necessary to include the -galactosidase gene in a BAC?
A. -galactosidase is a negative selectable marker.
B. -galactosidase is a positive selectable marker.
C. -galactosidase confers resistance to several antibiotics.
D. Presence of -galactosidase indicates cloned DNA segment is present.
E. Absence of -galactosidase indicates cloned DNA segment is present.
N-terminal sequences of four different bacterial proteins are listed below. Which of these proteins would have the shortest half-life?
A. Ala-Val-Ile----
B. Ser-Glu-Gly----
C. Lys-Gln-Pro----
D. Thr-Gly-Ala----
In response to the presence of extracellular antigen, B cells rapidly proliferate and the immunoglobulin M (IgM) proteins produced are soluble rather than anchored in the membrane.This change in IgM protein state is due to:
A. the cleavage of several hydrophobic amino acid residues from the IgM protein.
B. the differential expression of two different IgM genes.
C. the predominant use of the first 3' end cleavage site of the IgM pre-mRNA.
D. inclusion of the M exon in mature IgM mRNA.
Which of these processes is least likely to expand the coding capacity of the genome?
A. RNA editing
B. alternative splicing
C. poly(A) site choice
D. RNA capping
Tumor suppressor genes:
A. encode proteins that drive the cell cycle forward.
B. encode proteins that suppress development.
C. encode proteins that suppress cell division.
D. encode proteins that suppress DNA repair.
E. encode proteins that suppress metabolism.
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