The first genome sequenced was that of a :

The first genome sequenced was that of a
 
  A) virus.
  B) bacterium.
  C) eukaryote.
  D) archaeon.

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In general, prokaryotic genome size is correlated to lifestyle. Which type of prokaryote typically has the smallest genome?
 
  A) parasite
  B) endosymbiont
  C) autotroph
  D) free-living heterotroph

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Linking an ORF with a specific function is an example of gene
 
  A) annotation.
  B) assembly.
  C) codon bias.
  D) expression.

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The total genetic complement of ALL cells within a microbial community is called a(n)
 
  A) chromosomal island.
  B) interactome.
  C) metagenome.
  D) metabolome.

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A computer program recognizes an ORF by looking for ribosomal binding sites, start codons, and stop codons with an appropriate number of nucleotides between each element. What is a drawback of this approach?
 
  A) Too many ORFS are identified, most of which are stretches on non-coding junk DNA.
  B) Codon bias causes incorrect annotations.
  C) Unusual, but legitimate genes and non-coding RNA may be missed.
  D) We lack the computing power to complete the analyses in a timely manner, thus many genomes are only partially annotated.