What is the most important factor contributing to the onset of pulmonary hypertension in the pa-tient with COPD?
a. Alveolar hypoxia
b. Compression of pulmonary vasculature
c. Left ventricular failure
d. Loss of vascular surface
Q. 2 What IV infusion has been found to improve exercise capacity, hemodynamic variables, and sur-vival in patients with severe IPAH?
a. Bosentan
b. Epoprostenol
c. Methylprednisolone
d. Sildenafil
Q. 3 Why is the use of oxygen to maintain oxygen saturations greater than 90 particularly important in the management of idiopathic pulmonary artery hypertension?
a. These patients have a low cardiopulmo-nary reserve.
b. Low alveolar oxygen causes vasocon-striction.
c. Many patients have central cyanosis.
d. These patients are especially susceptible to tissue hypoxia.
Q. 4 Why are calcium-channel blockers not used in all patients with idiopathic pulmonary artery hy-pertension?
a. It causes severe side effects.
b. Many of these patients have systemic hy-potension.
c. Only a small percentage of IPAH patients respond.
d. There is a high incidence of anaphylaxis.
Q. 5 In what type of IPAH patient is lung transplantation indicated?
a. All pulmonary artery hypertension patients with clinically significant disease
b. Patients not responding to vasodilators with significant cardiac dysfunction
c. Patients with class II, class III, or class IV disease
d. Patients with refractory hypoxemia
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