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Armenb Armenb
wrote...
Posts: 570
Rep: 1 0
6 years ago
The process by which a drug is transported to its sites of action, eliminated, or stored is referred to as
 
  a. bioavailability.
  b. biotransformation.
  c. drug distribution.
  d. plasma half-life.



Q. 2  The time required for the plasma concentration of a drug to decrease by one-half is referred to as
 
  a. bioavailability.
  b. biotransformation.
  c. drug distribution.
  d. plasma half-life.



Q. 3  The term used to indicate the proportion of a drug that reaches the systemic circulation is
 
  a. bioavailability.
  b. biotransformation.
  c. pharmacokinetics.
  d. structure-activity relationship.



Q. 4  This term is used to describe when two drugs act on the same receptors and the combined effect is the simple linear sum of the effects of the two drugs, up to a maximal effect.
 
  a. Potency
  b. Hypersensitivity
  c. Potentiation
  d. Additivity



Q. 5  Why is lipid diffusion an important mechanism for drug absorption?
 
  a. Many epithelial membranes must be crossed if a drug is to distribute in the body and reach its target organ.
  b. Epithelial cells do not have lipid membranes, so a drug must be water-soluble to diffuse across such a membrane.
  c. It is directly related to the proportion of a drug that reaches the systemic circulation.
  d. Lipid diffusion has no importance in drug absorption because the body has very few epithelial membranes drugs must cross.



Q. 6  A special case of synergism in which one drug has no effect but can increase the activity of another drug is known as
 
  a. potency.
  b. hypersensitivity.
  c. potentiation.
  d. additivity.



Q. 7  Mr. Ashoor is a 29-year-old asthmatic patient who takes MDI albuterol for wheezing and typically gets quick relief following two puffs. After he mowed the lawn today, he realized he was having a rapid decrease in responsiveness to his albuterol.
 
  He tried taking it again but still had no relief. This situation is described by which of the following terms used to refer to drug responsiveness?
  a. Hypersensitivity
  b. Idiosyncratic effect
  c. Tolerance
  d. Tachyphylaxis



Q. 8  Which is the term that refers to the concentration (EC50) or dose (ED50) of a drug producing 50 of the maximal response of the drug?
 
  a. Potency
  b. Hypersensitivity
  c. Potentiation
  d. Additivity
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Replies
wrote...
6 years ago
(Answer to Q. 1)  ANS: C

(Answer to Q. 2)  ANS: D

(Answer to Q. 3)  ANS: A

(Answer to Q. 4)  ANS: D

(Answer to Q. 5)  ANS: A

(Answer to Q. 6)  ANS: C

(Answer to Q. 7)  ANS: D

(Answer to Q. 8)  ANS: A
Armenb Author
wrote...
6 years ago
This calls for a celebration Person Raising Both Hands in Celebration
wrote...
6 years ago
I get paid? lol

My pleasure
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