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colleen colleen
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Posts: 17077
12 years ago
Discuss the production of new analogs of existing antimicrobial compounds.
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Sunshine ☀ ☼

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Donated
Valued Member
12 years ago
Automated (computational) discovery of analogs involves combinatorial chemistry. Systematic modifications are made to a particular antimicrobial compound such as tetracycline and each are then tested for efficacy. For example, eight derivatives at each of five sites yield 32,768 (or 85) analogs to test.
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