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Rye18 Rye18
wrote...
2 years ago
Expound these:  

Many biological molecules are weak acids or weak bases.

The stronger the acid , the weaker its conjugate base.

Most biological  reaction occurs between  pH 6.5 and pH 8.0
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wrote...
2 years ago
Many biological molecules are weak acids or weak bases

True. Weak acids and weak bases have important applications in biochemical studies, chemistry reactions, and physiological purposes, particularly because of their role in buffer solutions. Weak bases can also be used to catalyze certain reactions.

Quote
The stronger the acid , the weaker its conjugate base.

True. Strong acids readily give up their protons, because the resulting conjugate base becomes more stable with respect to its new electron distribution. An example of this would be the acid halides with the exception of HF. The conjugate bases of these acids achieve their octets and diffuse polarizability, rendering them electronically stable.

Quote
Most biological  reaction occurs between  pH 6.5 and pH 8.0

True. This range is closest to neutral. Anything beyond this range leads to acidosis or alkalosis. Most buffer systems will reach equilibrium around this range. In addition, water that doesn't fall in the "safe" pH range of 6.5 to 8.5 can be problematic to an organism.
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