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5 months ago Edited: 5 months ago, whybookworm
Hello! Smiling Face with Open Mouth I am studying for my A-level Biology Main Cambridge exams and I have a question about ionic bonds in globular proteins and their denaturation. So, I know that ionic bonds can be broken by pH but I was wondering if it can also be broken by high temperatures?
Thank you.
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wrote...
Educator
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5 months ago
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Hi there,

The structure of a protein is governed by covalent bonds and hydrogen bonds mostly. Are you certain about "ionic bonds"? I know there's a possibility for ionic bonds to form in the tertiary structure, but it's not profound. Anyway, to answer your question, heat and pH are both denaturants.
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wrote...
5 months ago
Thank you!
Well in my A-level syllabus they don't mention it being less present or more present. They just say that ionic bond is one of the bonds between NH3 + and COO - and that they affect the 3-D structure.
But thanks for your answer
wrote...
Educator
5 months ago
Also be mindful that ionic bonds occur between metals and non-metals. Neither NH3+ and COO- are metals.
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5 months ago
https://www.google.mu/imgres?imgurl=https://www.easybiologyclass.com/wp-content/uploads/2017/01/structure-of-ionic-bonds-in-protein.jpg&imgrefurl=https://www.easybiologyclass.com/bonds-involved-in-protein-structure-and-conformation/&h=360&w=445&tbnid=ySARAgiEq6p6DM:&q=ionic+bonds+in+proteins&tbnh=160&tbnw=198&usg=AI4_-kRaCNF0xUnj_PtNxFpzKYLtZOdzXg&vet=12ahUKEwjIpfyq5IjfAhVLB8AKHRZ6A_YQ9QEwAHoECAcQBg..i&docid=BMNbkrQORaav-M&sa=X&ved=2ahUKEwjIpfyq5IjfAhVLB8AKHRZ6A_YQ9QEwAHoECAcQBg

Maybe this link could clear up any confusions?
wrote...
Educator
5 months ago
That's good to know, usually they ignore this in textbooks. Found something a little more informative too

http://earth.callutheran.edu/Academic_Programs/Departments/BioDev/omm/chymo/chymo.htm
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wrote...
5 months ago
Slight Smile That's nice. Glad to be of help and to receive help, thank you.
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