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4 months ago
A patient previously experienced an anaphylactic reaction to penicillin G. Which of the following medications should not be administered to this patient due to the potential for cross-sensitivity?
A)Lactulose (Chronulac)
B)Ketoconazole (Nizoral)
C)Kanamycin (Kantrex)
D)Cefadroxil (Duricef)
Textbook 
Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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4 months ago
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Cefadroxil (Duricef) is a cephalosporin. Administration of cephalosporins or carbapenems should be avoided if possible in people with life-threatening allergic reactions to penicillin. Lactulose reduces blood ammonia by resident intestinal bacteria. It is not contraindicated in the event of penicillin anaphylaxis. Ketoconazole is an antifungal and does not possess cross-sensitivity to penicillin. Kanamycin is an aminoglycoside and does not possess cross-sensitivity to penicillin.

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