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2 months ago
A patient is administered Augmentin (amoxicillin and clavulanate potassium) to treat otitis media. How does a beta-lactamase inhibitor agent achieve a therapeutic effect?
A)It extends the spectrum of antibacterial activity of penicillin.
B)It extends the spectrum of the beta-lactamase inhibitor.
C)It decreases the side effects of high-dose penicillin.
D)It increases the absorption of the penicillin.
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Abrams' Clinical Drug Therapy: Rationales for Nursing Practice
Edition: 10th
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2 months ago
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When combined with a penicillin, the beta-lactamase inhibitor protects the penicillin from destruction by the enzymes and extends the penicillin's spectrum of antimicrobial activity. Augmentin does not extend the spectrum of beta-lactamase inhibitor. Augmentin does not decrease the side effects of high-dose penicillin. Augmentin does not increase the absorption of penicillin.

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