A patient is diagnosed with heart failure. She asks the nurse for further details about heart ...

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Endothelial dysfunction allows processes that narrow the blood vessel lumen and lead to blood clot formation and vasoconstriction that further narrow the blood vessel lumen. These are major factors in coronary artery disease and hypertension, the most common conditions leading to heart failure. Hyperthyroidism, not hypothyroidism, is a cause of heart failure. The administration of diuretics decreases fluid volume, which prevents the symptoms of heart failure. The use of digoxin increases the force of myocardial contraction and prevents the development of congestive heart failure in patients whose heart cannot pump blood to meet tissue needs. A high-fat diet does not directly cause heart failure.