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wrote...
Educator
Top Poster
Posts: 25123
2 months ago
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This idea is the same for all cancer types. Except according to the article, the failure rate for pancreatic cancer is higher because pancreatic cells (as per the article) have high concentration of proteases in that tissue type. Proteases are enzymes that breakdown proteins; hence, it's likely digest the substance before it can be processed by the adaptive immune system cells.
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wrote...
Valued Member
2 months ago
https://medicalxpress.com/news/2010-10-scientists-cancer-purely-man-made.html

Thanks & Regards,
Prashant S Akerkar
wrote...
Staff Member
2 months ago

I can't seem to fully agree here because there's not one instance of proof that shows a normal cell becoming cancerous in the presence of a chemical. For example, we know that people who smoke cigarettes have a higher likelihood of developing lung disease, but they've never actually shown the toxins in the smoke making a cell "cancerous" in real-time. In fact, they can't even isolate a chemical within the smoke that'll cause it.

A statement like that is very easy to make, but very hard to prove clinically. You can get away with making statements like that by looking at historical database, but then you can say that the data is incomplete, so how's it valid? The article mentions:

Although this statistical construct is true, individuals in ancient Egypt and Greece did live long enough to develop such diseases as atherosclerosis, Paget's disease of bone, and osteoporosis, and, in modern populations, bone tumours primarily affect the young.

Which suggests that people back then didn't live long enough for cancer to be seen widely in the population. Also, genetics plays a major role in cancer too. Women who've inherited the mutated alleles of the brca1 gene are more likely to develop onset breast cancer than women who don't -- that has little to do with the environment.
- Master of Science in Biology
- Bachelor of Science (Biology)
- Bachelor of Education
wrote...
2 months ago
Cancer has many causative risk factors. Many of them are avoidable but human population is just not avoiding them in spite of in depth knowledge. Simple example is smoking,our life style and to add fast pace industrialisation increasing chemical carcinogens, food adulterations, etc.

I will put ,cancer is not man made disease as it has been there since ages but human population has knowingly or unknowingly added to continued occurrence.

Many factors are beyond our control.
wrote...
Valued Member
A month ago
Thanks.

https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/stem-cell-transplant.html

Stem cell transplants can help in curing certain types of cancer such as leukaemia ?

Thanks & Regards,
Prashant S Akerkar
wrote...
Educator
A month ago
Yes, specifically acute myeloid leukemia (AML), through bone marrow transplants (also known as blood stem cell transplants) . Healthy cells are obtained from a donor first (I remember it's extracted from the pelvic bone because it's spongy). Oftentimes the donor is a family member, though unrelated donor or umbilical cord blood (if stored from birth, for example) also works.

However, before the transplant, the recipient needs to get chemotherapy first - with or without radiation - to kill the unhealthy cells.
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wrote...
Valued Member
A month ago
Thank you.

https://www.linkedin.com/in/sanket-awate-47081080

This is a great profile. Post Doctoral fellow - Cancer biologist.

Thanks & Regards,
Prashant S Akerkar
wrote...
Educator
A month ago
Great resume 👍👍
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wrote...
Valued Member
3 weeks ago
Thanks.

https://www.google.com/search?q=cancer+disease&tbm=isch&ved=2ahUKEwiInvaeiqDkAhXA0nMBHSdABLkQ2-cCegQIABAC&oq=cancer+disease&gs_l=mobile-gws-wiz-img.12..0l5.11484.15843..17094...0.0..0.185.1474.0j10......0....1.........41j0i67.gKyEGlZD1Iw&ei=IpNjXYiFMMClz7sPp4CRyAs&bih=592&biw=360&prmd=inbv

I am highly optimistic that one day Cancer Vaccines will be available for all Human Being Organs.

Thanks & Regards,
Prashant S Akerkar
wrote...
Educator
3 weeks ago Edited: 3 weeks ago, bio_man

Sadly, I don't see that ever happening. The science behind prevention through vaccines doesn't apply to cancer because cancer is not something you can catch in the air, or transferable from person-to-person, or particularly caused by a pathogen.

However, if it were caused by a pathogen, such as a virus of bacteria, and we knew the specific part of that of that organism leads to cancer (such a protein within it), only then could we make a vaccine. For instance, we know HPV causes cervical cancer when left untreated, so we've made vaccines that are against HPV. Notice here we didn't make a cancer vaccine, but a cancer that's opposing the pathogen, which potentially can lead to the disease.

The issue is that very few pathogens are directly linked to cancer. In the case of cigarette smokers, there's a correlation between smoking and lung cancer. What vaccine could we make here? The smoke is poisonous no matter what protection you give your body.
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