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krakrakels krakrakels
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7 months ago
What defines the end of a eukaryotic gene?

▸ A 3' UTR of at least 25 nucleotides recruits an RNase that cleaves the pre-mRNA.

▸ There is no clearly defined end to eukaryotic genes, unlike for bacterial genes.

▸ A stem-loop structure in the transcriptional terminator region stalls the RNA polymerase.

▸ Presence of a stop codon leads to RNA polymerase stalling and ceasing transcription.

▸ Presence of a polyadenylation signal sequence leads to cleavage of the pre-mRNA.
Textbook 

Genetic Analysis: An Integrated Approach


Edition: 3rd
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brina10brina10
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Presence of a polyadenylation signal sequence leads to cleavage of the pre-mRNA.

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