Top Posters
Since Sunday
5
o
5
4
m
4
b
4
x
4
a
4
l
4
t
4
S
4
m
3
s
3
New Topic  
robbie robbie
wrote...
Posts: 90
Rep: 0 0
2 years ago
Which lists the potential steps for genetic therapy for mice with sickle cell disease (βSS) in the correct order?

I.Differentiation of iPS cells into hematopoietic progenitor (HP) cells by infecting with retrovirus 
expressing HoxB4.
II.Reprogramming tail fibroblasts into induced pluripotent stem (iPS) cells by infecting them with 
viral vectors containing transcription factors.
III.Infection with a viral vector expressing Cre recombinase to remove transcription factor(s) from 
from iPS cells.
IV.Transplantation of corrected (βA/βA) hematopoietic cells back into irradiated mice.
V.Homologous recombination with βS and wild-type βA allele via CRISPR-Cas9 genome editing.


▸ I, II, III, V, IV

▸ II, III, V, I, IV

▸ V, III, IV, I, II

▸ V, III, I, IV, II

▸ II, III, IV, V, I
Textbook 
Genetic Analysis: An Integrated Approach

Genetic Analysis: An Integrated Approach


Edition: 3rd
Authors:
Read 41 times
1 Reply
Replies
Answer verified by a subject expert
Andylai01Andylai01
wrote...
Posts: 87
Rep: 1 0
2 years ago
Sign in or Sign up in seconds to unlock everything for free
More solutions for this book are available here
1

Related Topics

robbie Author
wrote...

2 years ago
Good timing, thanks!
wrote...

Yesterday
Thanks for your help!!
wrote...

2 hours ago
Correct Slight Smile TY
New Topic      
Explore
Post your homework questions and get free online help from our incredible volunteers
  757 People Browsing
 114 Signed Up Today
Related Images
  
 404
  
 63
  
 2273
Your Opinion
How often do you eat-out per week?
Votes: 79