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Shea5927 Shea5927
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2 years ago
There is a hypothetical gene in mice that produces a substance that induces twitchiness in hind leg muscles. A female mouse of a true-breeding twitchy strain is mated with a male of a true-breeding non-twitchy strain. All progeny are twitchy. Twitchiness may simply be a dominant trait caused by a nuclear allele, or it could be due to mtDNA.  Which of these procedures would you use to provide evidence for your hypothesis that twitchiness is due to mtDNA?

▸ Sequence the mtDNA of the twitchy mother.

▸ Breed twitchy male progeny with normal females to show no paternal inheritance.

▸ Breed twitchy female with twitchy male F1 mice to verify there is maternal inheritance.

▸ Backcross twitchy female offspring with normal fathers.

▸ Sequence the mtDNA of the twitchy male offspring.
Textbook 
Genetic Analysis: An Integrated Approach

Genetic Analysis: An Integrated Approach


Edition: 3rd
Authors:
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works123works123
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